Plavix and Codeine sulfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plavix (clopidogrel bisulfate) and Codeine sulfate (codeine sulfate). Common drug interactions include diabetic retinopathy among females and abasia among males.

The phase IV clinical study analyzes what interactions people have when they take Plavix and Codeine sulfate. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Plavix?

Plavix has active ingredients of clopidogrel bisulfate. It is often used in stent. eHealthMe is studying from 151,178 Plavix users. Check the latest studies of Plavix.

What is Codeine sulfate?

Codeine sulfate has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 4,510 Codeine sulfate users. Check the latest studies of Codeine sulfate.



On Jul, 28, 2026

44 people who take Plavix and Codeine sulfate together, and have interactions are studied.

Plavix and Codeine sulfate drug interactions.

What are the common drug interactions of Plavix and Codeine Sulfate, by gender? *:

female:

  1. Diabetic retinopathy (damage to the retina caused by complications of diabetes)
  2. Diastolic dysfunction
  3. Dyspepsia (indigestion)
  4. Early satiety (feeling full before completing a normal sized meal)
  5. Emotional disorder
  6. Erythema (redness of the skin)
  7. Eustachian tube dysfunction (eustachian tube problems like clearing the ears when flying, suffering infection, and recurring ear infection)
  8. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
  9. Eyelid ptosis (falling of the upper or lower eyelid)
  10. Fibromyalgia (a long-term condition which causes pain all over the body)

male:

  1. Abasia (inability to walk)
  2. Asthenia (weakness)
  3. Skin irritation
  4. Sleep disorder
  5. Vomiting
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  8. Cerebrovascular disorder (disease of brain)
  9. Chronic kidney disease
  10. Death

What are the common drug interactions of Plavix and Codeine Sulfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Oedema peripheral (superficial swelling)
  2. Abdominal pain
  3. Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
  4. Anxiety
  5. Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
  6. Arthralgia (joint pain)
  7. Asthma
  8. Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
  9. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  10. Blood glucose decreased

50-59:

  1. Abdominal discomfort
  2. Chronic kidney disease
  3. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  4. Anxiety
  5. Blood glucose increased
  6. Depression
  7. Diabetic nephropathy (diabetic kidney disease)
  8. Dizziness
  9. Dyspnoea exertional (breathlessness or shortness of breath)
  10. Fall

60+:

  1. Asthenia (weakness)
  2. Fatigue (feeling of tiredness)
  3. Anaemia (lack of blood)
  4. Cardiomegaly (increased size of heart than normal)
  5. Dizziness
  6. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  7. Oedema peripheral (superficial swelling)
  8. Renal failure acute (rapid kidney dysfunction)
  9. Urinary tract infection
  10. Constipation

What are the existing conditions these people have? *

  1. High Blood Pressure: 11 people, 25.00%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 25.00%
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints): 10 people, 22.73%
  4. High Blood Cholesterol: 8 people, 18.18%
  5. Diabetes: 8 people, 18.18%
  6. Cardiac Disorder: 7 people, 15.91%
  7. Psoriasis (immune-mediated disease that affects the skin): 6 people, 13.64%
  8. Fungal Infection: 6 people, 13.64%
  9. Nausea (feeling of having an urge to vomit): 5 people, 11.36%
  10. Cough: 5 people, 11.36%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Plavix and Codeine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Plavix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Codeine sulfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Plavix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Codeine sulfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on clopidogrel bisulfate and codeine sulfate (the active ingredients of Plavix and Codeine sulfate, respectively), and Plavix and Codeine sulfate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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