Aceon and Pain exacerbated - a phase IV clinical study of FDA data

Summary:

Pain exacerbated is reported as a side effect among people who take Aceon (perindopril erbumine), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Pain exacerbated when taking Aceon. It is created by eHealthMe based on reports of 1,743 people who have side effects when taking Aceon from the FDA, and is updated regularly.

What is Aceon?

Aceon has active ingredients of perindopril erbumine. It is often used in high blood pressure. eHealthMe is studying from 1,785 Aceon users. Check the latest studies of Aceon.

What is Pain exacerbated?

Pain exacerbated is found to be associated with 3,978 drugs and 3,029 conditions by eHealthMe. Check the latest studies of Pain exacerbated.



On Jul, 28, 2026

1,743 people reported to have side effects when taking Aceon.
Among them, 59 people (3.38%) have Pain exacerbated.

Could Aceon cause Pain exacerbated?

Among these 59 people:

How long have people been on Aceon when they have Pain exacerbated? *

  • < 1 month: 25.0 %
  • 1 - 6 months: 25.0 %
  • 6 - 12 months: 12.5 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 37.5 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Pain exacerbated when taking Aceon? *

  • female: 67.8 %
  • male: 32.2 %

What is the age of people who have Pain exacerbated when taking Aceon? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 1.69 %
  • 30-39: 0.0 %
  • 40-49: 20.34 %
  • 50-59: 11.86 %
  • 60+: 66.1 %

What are other drugs people take besides Aceon? *

  1. Vioxx: 23 people, 38.98%
  2. Zometa: 23 people, 38.98%
  3. Ambien: 20 people, 33.90%
  4. Ativan: 19 people, 32.20%
  5. Celebrex: 18 people, 30.51%
  6. Paxil: 18 people, 30.51%
  7. Lovenox: 18 people, 30.51%
  8. Nexium: 17 people, 28.81%
  9. Aredia: 17 people, 28.81%
  10. Percocet: 16 people, 27.12%

What are other side effects people have besides Pain exacerbated? *

  1. Stress And Anxiety: 29 people, 49.15%
  2. Rashes (redness): 27 people, 45.76%
  3. Pain In Extremity: 25 people, 42.37%
  4. Back Pain: 24 people, 40.68%
  5. Pain In Jaw: 23 people, 38.98%
  6. Hypoaesthesia (reduced sense of touch or sensation): 21 people, 35.59%
  7. Primary Sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone): 21 people, 35.59%
  8. Emotional Distress: 21 people, 35.59%
  9. Bone Disorder: 20 people, 33.90%
  10. Weakness: 18 people, 30.51%

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 15 people, 25.42%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 23.73%
  3. Stress And Anxiety: 14 people, 23.73%
  4. Bone Pain: 14 people, 23.73%
  5. Breast Cancer: 14 people, 23.73%
  6. Breast Cancer Metastatic: 7 people, 11.86%
  7. Multiple Myeloma (cancer of the plasma cells): 7 people, 11.86%
  8. Tendonitis (a condition that causes pain and swelling of tendons): 2 people, 3.39%
  9. Fungal Skin Infection: 2 people, 3.39%
  10. Thyroid Diseases: 1 person, 1.69%

* Approximation only. Some reports may have incomplete information.

Do you take Aceon and have Pain exacerbated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aceon:

Pain exacerbated treatments and more:

How severe was Pain exacerbated and when was it recovered:

Expand to all the drugs that have ingredients of perindopril erbumine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aceon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain exacerbated:

Browse all the conditions that are associated with Pain exacerbated:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on perindopril erbumine (the active ingredients of Aceon) and Aceon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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