Plavix and Euthyrox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plavix (clopidogrel bisulfate) and Euthyrox (levothyroxine sodium). Common drug interactions include colitis haemorrhagic among females and blood creatinine increased among males.

The phase IV clinical study analyzes what interactions people have when they take Plavix and Euthyrox. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Plavix?

Plavix has active ingredients of clopidogrel bisulfate. It is often used in stent. eHealthMe is studying from 151,178 Plavix users. Check the latest studies of Plavix.

What is Euthyrox?

Euthyrox has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,740 Euthyrox users. Check the latest studies of Euthyrox.



On Jul, 17, 2026

79 people who take Plavix and Euthyrox together, and have interactions are studied.

Plavix and Euthyrox drug interactions.

What are the common drug interactions of Plavix and Euthyrox, by gender? *:

female:

  1. Colitis haemorrhagic (bleeding diarrhoea due to infection of colon)
  2. Colitis ulcerative (inflammation of colon with ulcer)
  3. Conjunctivitis (pink eye)
  4. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  5. Dehydration (dryness resulting from the removal of water)
  6. Dyspnoea exertional (breathlessness or shortness of breath)
  7. Eye irritation
  8. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  9. Gastrointestinal motility disorder (abnormal intestinal contractions)
  10. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

male:

  1. Blood creatinine increased
  2. Haematoma (collection of blood outside the blood vessels)
  3. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  4. Alopecia (absence of hair from areas of the body)
  5. Angioedema (rapid swelling of the dermis)
  6. Blood triglycerides increased
  7. Blood urea increased
  8. C-reactive protein increased
  9. Cardiomyopathy (weakening of the heart muscle)
  10. Cellulitis (infection under the skin)

What are the common drug interactions of Plavix and Euthyrox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Transplant failure (transplantation failed to meet outcome)
  2. Acute hepatic failure
  3. Chest pain
  4. Coagulation time prolonged
  5. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  6. Cough
  7. Haemorrhagic diathesis (bleeding tendency)
  8. Hepatic steatosis (fatty liver disease)
  9. Hypotension (abnormally low blood pressure)
  10. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

60+:

  1. General physical health deterioration (weak health status)
  2. Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
  3. Disturbance in attention
  4. Encephalitis (inflammation of the brain)
  5. Enterococcal infection
  6. Hepatic enzyme increased
  7. Meningitis tuberculous (a bacterial infection of the membranes covering the brain and spinal cord (meninges))
  8. Peroneal nerve palsy
  9. Psychotic disorder
  10. Pulmonary tuberculosis (lungs tuberculosis)

What are the existing conditions these people have? *

  1. High Blood Pressure: 22 people, 27.85%
  2. Type 2 Diabetes: 17 people, 21.52%
  3. High Blood Cholesterol: 16 people, 20.25%
  4. Weakness: 10 people, 12.66%
  5. Osteoporosis (bones weak and more likely to break): 10 people, 12.66%
  6. Endocarditis (inflammation in heart muscle): 10 people, 12.66%
  7. Breast Cancer Metastatic: 8 people, 10.13%
  8. Diffuse Large B-Cell Lymphoma Stage Iv (cancer of b cells, a type of white blood cell-stage iv): 6 people, 7.59%
  9. Temporal Arteritis (inflammation and damage to blood vessels that supply the head area): 5 people, 6.33%
  10. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 5.06%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Plavix and Euthyrox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Plavix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Euthyrox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Plavix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Euthyrox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on clopidogrel bisulfate and levothyroxine sodium (the active ingredients of Plavix and Euthyrox, respectively), and Plavix and Euthyrox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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