Plavix and Protelos drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plavix (clopidogrel bisulfate) and Protelos (strontium ranelate). Common drug interactions include aspartate aminotransferase increased among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Plavix and Protelos. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Plavix?

Plavix has active ingredients of clopidogrel bisulfate. It is often used in stent. eHealthMe is studying from 151,178 Plavix users. Check the latest studies of Plavix.

What is Protelos?

Protelos has active ingredients of strontium ranelate. It is often used in osteoporosis. eHealthMe is studying from 302 Protelos users. Check the latest studies of Protelos.



On Jul, 27, 2026

12 people who take Plavix and Protelos together, and have interactions are studied.

Plavix and Protelos drug interactions.

What are the common drug interactions of Plavix and Protelos, by gender? *:

female:

  1. Aspartate aminotransferase increased
  2. Back pain
  3. Blood lactate dehydrogenase increased
  4. Blood thyroid stimulating hormone increased
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Contusion (a type of hematoma of tissue in which capillaries)
  7. Cough
  8. Death
  9. Dyspnoea (difficult or laboured respiration)
  10. Dysstasia (difficulty in standing)

male:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Clumsiness (a lack of coordination or elegance)
  3. Fall
  4. Respiratory rate decreased (less breathing rate/min)
  5. Somnolence (a state of near-sleep, a strong desire for sleep)
  6. Suicide attempt

What are the common drug interactions of Plavix and Protelos, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Abasia (inability to walk)
  2. Alanine aminotransferase increased
  3. Arthralgia (joint pain)
  4. Aspartate aminotransferase increased
  5. Back pain
  6. Blood lactate dehydrogenase increased
  7. Blood thyroid stimulating hormone increased
  8. Dysstasia (difficulty in standing)
  9. Gamma-glutamyltransferase increased
  10. Glomerular filtration rate decreased

60+:

  1. Osteitis deformans (a disease of bone occurring in the middle aged and elderly; excessive bone destruction sometimes leading to bone pain)
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Osteonecrosis (death of bone)
  4. Pleural fibrosis (formation of fibrous tissue in lung)
  5. Pruritus (severe itching of the skin)
  6. Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
  7. Vascular purpura (haemorrhages in the skin and mucous membranes that result in the appearance of purplish spots or patches)
  8. Contusion (a type of hematoma of tissue in which capillaries)
  9. Cough
  10. Death

What are the existing conditions these people have? *

  1. Pain: 3 people, 25.00%
  2. Depression: 3 people, 25.00%
  3. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 16.67%
  4. Gastric Disorder (disease of stomach): 2 people, 16.67%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 16.67%
  6. Promotion Of Peripheral Circulation: 2 people, 16.67%
  7. Sleep Disorder: 2 people, 16.67%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
  9. Bronchial Obstruction (blockage of the breathing passages to the lungs): 1 person, 8.33%
  10. Chronic Thyroiditis (long lasting inflammation of thyroid gland): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Plavix and Protelos?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Plavix and Protelos:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Plavix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Protelos:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Plavix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Protelos and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on clopidogrel bisulfate and strontium ranelate (the active ingredients of Plavix and Protelos, respectively), and Plavix and Protelos (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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