Plegridy and Centrum silver drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Plegridy (peginterferon beta-1a) and Centrum silver (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include influenza like illness among females.

The phase IV clinical study analyzes what interactions people have when they take Plegridy and Centrum silver. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Plegridy?

Plegridy has active ingredients of peginterferon beta-1a. eHealthMe is studying from 14,764 Plegridy users. Check the latest studies of Plegridy.

What is Centrum silver?

Centrum silver has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 19,997 Centrum silver users. Check the latest studies of Centrum silver.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 21, 2026

13 people who take Plegridy and Centrum silver together, and have interactions are studied.

Plegridy and Centrum silver drug interactions.

What are the common drug interactions of Plegridy and Centrum Silver, by gender? *:

female:

  1. Influenza like illness
  2. Injection site erythema (redness at injection site)
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Hypersensitivity
  5. Injection site pain
  6. Neoplasm malignant (cancer tumour)
  7. Pulmonary hypertension (increase in blood pressure in the lung artery)
  8. White blood cell count decreased
  9. Erythema (redness of the skin)
  10. Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)

male:

n/a

What are the common drug interactions of Plegridy and Centrum Silver, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Hypersensitivity

60+:

  1. Drug ineffective
  2. Erythema (redness of the skin)
  3. Influenza like illness
  4. Injection site bruising
  5. Injection site erythema (redness at injection site)
  6. Injection site haematoma (localized swelling filled with blood at injection site)
  7. White blood cell count decreased
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 11 people, 84.62%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 30.77%
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 30.77%
  4. High Blood Pressure: 4 people, 30.77%
  5. Gait Disturbance: 3 people, 23.08%
  6. Micturition Disorder (disease of passing urine): 2 people, 15.38%
  7. Depression: 2 people, 15.38%
  8. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 7.69%
  9. Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Plegridy and Centrum silver?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Plegridy and Centrum silver:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Plegridy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Centrum silver:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Plegridy and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Centrum silver and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on peginterferon beta-1a and ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Plegridy and Centrum silver, respectively), and Plegridy and Centrum silver (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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