Posaconazole and Guaifenesin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Posaconazole (posaconazole) and Guaifenesin (guaifenesin). Common drug interactions include death among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Posaconazole and Guaifenesin. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Posaconazole?

Posaconazole has active ingredients of posaconazole. eHealthMe is studying from 9,475 Posaconazole users. Check the latest studies of Posaconazole.

What is Guaifenesin?

Guaifenesin has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 12,106 Guaifenesin users. Check the latest studies of Guaifenesin.

On Jul, 09, 2026

36 people who take Posaconazole and Guaifenesin together, and have interactions are studied.

Posaconazole and Guaifenesin drug interactions.

What are the common drug interactions of Posaconazole and Guaifenesin, by gender? *:

female:

Death
Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
Febrile neutropenia (fever with reduced white blood cells)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Fluid overload (too much fluid in the blood)
Abdominal pain upper
Alanine aminotransferase increased
Aspartate aminotransferase increased
Pleural effusion (water on the lungs)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)

male:

Death
Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
Erythema (redness of the skin)
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
Gout (uric acid crystals building up in the body)
Haematoma (collection of blood outside the blood vessels)
Haemorrhage (bleeding)
Headache (pain in head)
Hypertension (high blood pressure)
Hypokalaemia (low potassium)

What are the common drug interactions of Posaconazole and Guaifenesin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Bone marrow failure
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)

30-39:

Decreased appetite
Headache (pain in head)
Pyrexia (fever)
Red blood cell count decreased
White blood cell count decreased

40-49:

Abdominal pain upper
Alanine aminotransferase increased
Aspartate aminotransferase increased
Pleural effusion (water on the lungs)
Lymphadenopathy (disease or enlargement of lymph nodes)

50-59:

Death
Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
Arthralgia (joint pain)
Back pain
Blood creatinine increased
Brain abscess
Chest pain
Dyspnoea (difficult or laboured respiration)
Electric shock
Erythema (redness of the skin)

60+:

Asthenia (weakness)
Dehydration (dryness resulting from the removal of water)
Chronic lymphocytic leukaemia transformation (white blood cell cancer changes in fast growing cancer in lymph node)
Fatigue (feeling of tiredness)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hospitalisation
Infection
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Syncope (loss of consciousness with an inability to maintain postural tone)

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 21 people, 58.33%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 11.11%
Pain: 4 people, 11.11%
Nausea (feeling of having an urge to vomit): 4 people, 11.11%
Nausea And Vomiting: 3 people, 8.33%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.33%
Fever: 3 people, 8.33%
Diarrhea: 3 people, 8.33%
Insomnia (sleeplessness): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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