Potassium citrate and Diphenhydramine hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Potassium citrate (potassium citrate) and Diphenhydramine hydrochloride (diphenhydramine hydrochloride). Common drug interactions include cellulitis among females and pathological fracture among males.

The phase IV clinical study analyzes what interactions people have when they take Potassium citrate and Diphenhydramine hydrochloride. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Potassium citrate?

Potassium citrate has active ingredients of potassium citrate. It is often used in kidney stones. eHealthMe is studying from 5,909 Potassium citrate users. Check the latest studies of Potassium citrate.

What is Diphenhydramine hydrochloride?

Diphenhydramine hydrochloride has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 26,097 Diphenhydramine hydrochloride users. Check the latest studies of Diphenhydramine hydrochloride.

On Jul, 10, 2026

63 people who take Potassium citrate and Diphenhydramine hydrochloride together, and have interactions are studied.

Potassium citrate and Diphenhydramine hydrochloride drug interactions.

What are the common drug interactions of Potassium Citrate and Diphenhydramine Hydrochloride, by gender? *:

female:

Cellulitis (infection under the skin)
Localised infection (infection at the single location)
Lymphadenopathy (disease or enlargement of lymph nodes)
Neck pain
Respiratory tract infection
Stress
Vomiting
Fungal infection
Infusion site bruising
Anaphylactic reaction (serious allergic reaction)

male:

Pathological fracture (broken bone caused by disease)
Death
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Feeling hot
Gait disturbance
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Infection
Infusion related reaction
Joint swelling
Mouth haemorrhage (bleeding from mouth)

What are the common drug interactions of Potassium Citrate and Diphenhydramine Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Blood pressure decreased
Eating disorder
Fatigue (feeling of tiredness)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
General physical health deterioration (weak health status)
Infusion related reaction
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pain
Panic attack
Weight decreased

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Pain
Partner stress
Renal failure (kidney dysfunction)

40-49:

Arthralgia (joint pain)
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Asthenia (weakness)
Cataract (clouding of the lens inside the eye)
Cellulitis (infection under the skin)
Cystitis (inflammation of the wall of the bladder)
Dyspnoea (difficult or laboured respiration)
Fall
Fatigue (feeling of tiredness)
Headache (pain in head)

50-59:

Abdominal distension
Confusional state
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Dry mouth
Ear disorder
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Infusion site mass

60+:

Pathological fracture (broken bone caused by disease)
Pneumonia
Catheter site erythema (redness of skin at catheter site)
Erythema (redness of the skin)
Hereditary angioedema (recurrent episodes of severe swelling)
Hypersensitivity
Rash
Rash papular (redness with papule)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Contusion (a type of hematoma of tissue in which capillaries)

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 13 people, 20.63%
Hypokalemia (low potassium): 11 people, 17.46%
Immunodeficiency Common Variable: 9 people, 14.29%
Fever: 9 people, 14.29%
Urination - Excessive Volume: 9 people, 14.29%
Productive Cough: 8 people, 12.70%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 12.70%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 9.52%
Venous Thrombosis (blood clot (thrombus) that forms within a vein): 5 people, 7.94%
Itching: 5 people, 7.94%

* Approximation only. Some reports may have incomplete information.

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