Potassium phosphate and Nexium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Potassium phosphate (potassium) and Nexium (esomeprazole magnesium). Common drug interactions include renal failure among females and pleural effusion among males.

The phase IV clinical study analyzes what interactions people have when they take Potassium phosphate and Nexium. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Potassium phosphate?

Potassium phosphate has active ingredients of potassium. eHealthMe is studying from 578 Potassium phosphate users. Check the latest studies of Potassium phosphate.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,678 Nexium users. Check the latest studies of Nexium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

25 people who take Potassium phosphate and Nexium together, and have interactions are studied.

Potassium phosphate and Nexium drug interactions.

What are the common drug interactions of Potassium Phosphate and Nexium, by gender? *:

female:

Renal failure (kidney dysfunction)
Chronic kidney disease
Septic shock (shock due to blood infection)
Renal impairment (severely reduced kidney function)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Pyrexia (fever)
Respiratory failure (inadequate gas exchange by the respiratory system)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
White blood cell count decreased

male:

Pleural effusion (water on the lungs)
Constipation
Thrombocytopenia (decrease of platelets in blood)
Chronic kidney disease
Antidepressant drug level increased
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Hyperkalaemia (damage to or disease of the kidney)
Pneumonia
Renal failure (kidney dysfunction)

What are the common drug interactions of Potassium Phosphate and Nexium, by age (0-1 to 60+)? *:

0-1:

Abdominal compartment syndrome (increased pressure in abdomen)
Ascites (accumulation of fluid in the abdominal cavity)
Blood lactic acid increased
Cholecystitis (infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Coagulopathy (blood's ability to clot is impaired)
Duodenal perforation (complication of duodenal ulcer)
Enterococcal infection
Fluid retention (an abnormal accumulation of fluid in the blood)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

2-9:

Bradycardia (abnormally slow heart action)
Cardiac arrest
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Oxygen saturation decreased
Pyrexia (fever)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

10-19:

Coagulopathy (blood's ability to clot is impaired)
Multi-organ failure (multisystem organ failure)
Neurological symptom (symptoms of nervous system disease)
Pancreatitis necrotising (inflammation of the pancreas cause death of tissue in pancreas)
Respiratory failure (inadequate gas exchange by the respiratory system)

20-29:

n/a

30-39:

n/a

40-49:

Acute respiratory failure
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Renal failure (kidney dysfunction)
Septic shock (shock due to blood infection)

50-59:

Fungal sepsis (whole body infection by fungus)
Chronic kidney disease
Renal failure (kidney dysfunction)

60+:

Pleural effusion (water on the lungs)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Febrile neutropenia (fever with reduced white blood cells)
Hyperkeratosis (thickening of the outer layer of the skin)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Septic shock (shock due to blood infection)
Thrombocytopenia (decrease of platelets in blood)
White blood cell count decreased

What are the existing conditions these people have? *

High Blood Pressure: 9 people, 36.00%
Depression: 8 people, 32.00%
Pain: 7 people, 28.00%
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 6 people, 24.00%
Indigestion: 6 people, 24.00%
Muscle Spasms (muscle contraction): 5 people, 20.00%
Stress And Anxiety: 5 people, 20.00%
Diabetes: 5 people, 20.00%
Constipation: 5 people, 20.00%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 16.00%

* Approximation only. Some reports may have incomplete information.

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