Pramine and Armour thyroid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pramine (imipramine hydrochloride) and Armour thyroid (thyroid tablets, usp). Common drug interactions include fatigue among females and change of bowel habit among males.

The phase IV clinical study analyzes what interactions people have when they take Pramine and Armour thyroid. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Pramine?

Pramine has active ingredients of imipramine hydrochloride. eHealthMe is studying from 7,461 Pramine users. Check the latest studies of Pramine.

What is Armour thyroid?

Armour thyroid has active ingredients of thyroid tablets, usp. It is often used in hypothyroidism. eHealthMe is studying from 11,975 Armour thyroid users. Check the latest studies of Armour thyroid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

17 people who take Pramine and Armour thyroid together, and have interactions are studied.

Pramine and Armour thyroid drug interactions.

What are the common drug interactions of Pramine and Armour Thyroid, by gender? *:

female:

Fatigue (feeling of tiredness)
Abdominal discomfort
Alcoholism (problems with alcohol)
Asthenia (weakness)
Blood oestrogen increased
Blood pressure decreased
Depression
Disability
Disturbance in attention
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)

male:

Change of bowel habit
Arthralgia (joint pain)
Fatigue (feeling of tiredness)
Headache (pain in head)

What are the common drug interactions of Pramine and Armour Thyroid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Change of bowel habit

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Blood pressure decreased
Dizziness
Eye pruritus (eye itching)
Eyelid pain
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Inflammation
Joint swelling
Lacrimation decreased
Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
Ocular hyperaemia (an abnormally large amount of blood in eye)

What are the existing conditions these people have? *

Pain: 7 people, 41.18%
Thyroid Diseases: 4 people, 23.53%
Infection: 3 people, 17.65%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 17.65%
Actinic Keratosis (skin disease due to sun exposure): 2 people, 11.76%
Multiple Allergies (allergy to multiple agents): 2 people, 11.76%
Migraine (headache): 2 people, 11.76%
Joint Pain: 2 people, 11.76%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 11.76%
Cough: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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