Pramine and Ceftriaxone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pramine (imipramine hydrochloride) and Ceftriaxone (ceftriaxone sodium). Common drug interactions include chest discomfort among females and drug level increased among males.

The phase IV clinical study analyzes what interactions people have when they take Pramine and Ceftriaxone. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Pramine?

Pramine has active ingredients of imipramine hydrochloride. eHealthMe is studying from 7,461 Pramine users. Check the latest studies of Pramine.

What is Ceftriaxone?

Ceftriaxone has active ingredients of ceftriaxone sodium. It is often used in typhoid fever. eHealthMe is studying from 40,991 Ceftriaxone users. Check the latest studies of Ceftriaxone.

On Aug, 11, 2026

21 people who take Pramine and Ceftriaxone together, and have interactions are studied.

Pramine and Ceftriaxone drug interactions.

What are the common drug interactions of Pramine and Ceftriaxone, by gender? *:

female:

Chest discomfort
Dyspnoea (difficult or laboured respiration)
Electrocardiogram qt corrected interval prolonged
Electrocardiogram qt prolonged
Blood creatinine increased
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypokalaemia (low potassium)
Pyelonephritis (inflammation of kidney caused by bacteria)
Renal failure (kidney dysfunction)

male:

Drug level increased
Abdominal pain
Dyspnoea (difficult or laboured respiration)
Gingivitis (inflammation of gums)
Haemoglobin decreased
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Hypotension (abnormally low blood pressure)
Pain
Pyrexia (fever)
Renal failure (kidney dysfunction)

What are the common drug interactions of Pramine and Ceftriaxone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Arthralgia (joint pain)
Back pain
Blood lactate dehydrogenase increased
Blood pressure decreased
Blood pressure increased
Chest pain
Dyspnoea (difficult or laboured respiration)
Gingivitis (inflammation of gums)
Haemoglobin decreased

30-39:

n/a

40-49:

Chest discomfort
Dyspnoea (difficult or laboured respiration)
Electrocardiogram qt corrected interval prolonged
Electrocardiogram qt prolonged
Blood creatinine increased
Hypokalaemia (low potassium)
Pyelonephritis (inflammation of kidney caused by bacteria)

50-59:

Chronic kidney disease
Confusional state
Depression
Device occlusion
Loss of consciousness
Memory impairment
Renal failure (kidney dysfunction)
Stoma site abscess (a pus formation at abdominal opening)
Throat irritation
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

60+:

Drug level increased
Chronic kidney disease
Concussion (short loss of normal brain function in response to a head injury)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypotension (abnormally low blood pressure)
Renal failure (kidney dysfunction)
Somnolence (a state of near-sleep, a strong desire for sleep)
Drug level above therapeutic
Neoplasm malignant (cancer tumour)
Syncope (loss of consciousness with an inability to maintain postural tone)

What are the existing conditions these people have? *

Kidney Infection (Pyelonephritis): 6 people, 28.57%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 14.29%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 9.52%
Pain: 2 people, 9.52%
Depression: 2 people, 9.52%
Bladder Spasm: 2 people, 9.52%
Arthropathy: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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