Pramosone and Alprazolam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pramosone (hydrocortisone acetate; pramoxine hydrochloride) and Alprazolam (alprazolam). Common drug interactions include headache among females and blood creatinine increased among males.

The phase IV clinical study analyzes what interactions people have when they take Pramosone and Alprazolam. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Pramosone?

Pramosone has active ingredients of hydrocortisone acetate; pramoxine hydrochloride. eHealthMe is studying from 167 Pramosone users. Check the latest studies of Pramosone.

What is Alprazolam?

Alprazolam has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 134,864 Alprazolam users. Check the latest studies of Alprazolam.

On Jul, 14, 2026

11 people who take Pramosone and Alprazolam together, and have interactions are studied.

Pramosone and Alprazolam drug interactions.

What are the common drug interactions of Pramosone and Alprazolam, by gender? *:

female:

Headache (pain in head)
Intervertebral disc protrusion (spinal disc protrusion)
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Pruritus generalised (generalized itching)
Scar
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Somatisation disorder (a long-term (chronic) condition in which a person has physical symptoms that involve more than one part of the body)

male:

Blood creatinine increased
Cellulitis (infection under the skin)
Acute respiratory distress syndrome
Acute respiratory failure
Renal failure (kidney dysfunction)

What are the common drug interactions of Pramosone and Alprazolam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

30-39:

n/a

40-49:

n/a

50-59:

Blood creatinine increased
Cellulitis (infection under the skin)
Acute respiratory distress syndrome
Acute respiratory failure
Breast cancer
Depression
Renal failure (kidney dysfunction)
Somatisation disorder (a long-term (chronic) condition in which a person has physical symptoms that involve more than one part of the body)

60+:

Anaemia (lack of blood)
Arthralgia (joint pain)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Headache (pain in head)
Intervertebral disc protrusion (spinal disc protrusion)
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Pruritus generalised (generalized itching)

What are the existing conditions these people have? *

Premenstrual Syndrome: 2 people, 18.18%
High Blood Pressure: 2 people, 18.18%
Birth Control: 2 people, 18.18%
Acne (skin problems that cause pimples): 2 people, 18.18%
Migraine (headache): 1 person, 9.09%
High Blood Cholesterol: 1 person, 9.09%
Headache (pain in head): 1 person, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 9.09%
Asthma: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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