Prandin and Diflucan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prandin (repaglinide) and Diflucan (fluconazole). Common drug interactions include gastrooesophageal reflux disease among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Prandin and Diflucan. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Prandin?

Prandin has active ingredients of repaglinide. It is often used in diabetes. eHealthMe is studying from 4,680 Prandin users. Check the latest studies of Prandin.

What is Diflucan?

Diflucan has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 28,471 Diflucan users. Check the latest studies of Diflucan.

On Jul, 10, 2026

67 people who take Prandin and Diflucan together, and have interactions are studied.

What are the common drug interactions of Prandin and Diflucan, by gender? *:

female:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Exostosis (formation of new bone on the surface of a bone)
Gingival pain (gum pain)
Oedema peripheral (superficial swelling)
Osteitis (a general term for inflammation of bone)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Spinal osteoarthritis (joint cartilage loss in spine)
Swelling face

male:

Diarrhoea
Dehydration (dryness resulting from the removal of water)
Hypokalaemia (low potassium)
Intervertebral disc degeneration (spinal disc degeneration)
Lethargy (tiredness)
Muscular weakness (muscle weakness)
Oedema peripheral (superficial swelling)
Cellulitis (infection under the skin)
Febrile neutropenia (fever with reduced white blood cells)
General physical health deterioration (weak health status)

What are the common drug interactions of Prandin and Diflucan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Injury
Pain

30-39:

n/a

40-49:

Fungal infection
Hypersensitivity
Nausea (feeling of having an urge to vomit)
Oedema lower limb (fluid collection in tissue of lower leg)
Pain in limb
Pyrexia (fever)
Renal failure acute (rapid kidney dysfunction)
Urticaria (rash of round, red welts on the skin that itch intensely)

50-59:

Pain
Renal failure (kidney dysfunction)
Appendicitis (inflammation of the appendix)
Aptyalism (deficiency or absence of saliva)
Bone disorder
Bone erosion
Bone fragmentation
Bone pain
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
Cellulitis (infection under the skin)

60+:

Diarrhoea
Dehydration (dryness resulting from the removal of water)
Fall
Gait disturbance
Hypokalaemia (low potassium)
Intervertebral disc degeneration (spinal disc degeneration)
Lethargy (tiredness)
Muscular weakness (muscle weakness)
Oedema peripheral (superficial swelling)
Febrile neutropenia (fever with reduced white blood cells)

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 26 people, 38.81%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 25 people, 37.31%
Thrombocytopenia (decrease of platelets in blood): 11 people, 16.42%
Hypersensitivity: 7 people, 10.45%
Metastatic Neoplasm (spreadable cancer tumour): 6 people, 8.96%
High Blood Pressure: 6 people, 8.96%
Breast Cancer Metastatic: 6 people, 8.96%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 5 people, 7.46%
Enlarged Prostate: 5 people, 7.46%
Pain: 4 people, 5.97%

* Approximation only. Some reports may have incomplete information.

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