Prednisolone and Choline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prednisolone (prednisolone) and Choline (choline). Common drug interactions include coma among females and blood glucose increased among males.

The phase IV clinical study analyzes what interactions people have when they take Prednisolone and Choline. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.

What is Choline?

Choline has active ingredients of choline. eHealthMe is studying from 1,037 Choline users. Check the latest studies of Choline.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 04, 2026

60 people who take Prednisolone and Choline together, and have interactions are studied.

Prednisolone and Choline drug interactions.

What are the common drug interactions of Prednisolone and Choline, by gender? *:

female:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Diarrhoea
  6. Nausea (feeling of having an urge to vomit)
  7. Drug ineffective
  8. Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
  9. Rash
  10. Swelling face

male:

  1. Blood glucose increased
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  4. Subcutaneous emphysema (smooth bulging of the skin)
  5. Tracheal injury (injury to trachea)
  6. Blood pressure systolic decreased
  7. Blood sodium increased
  8. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  9. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  10. Septic shock (shock due to blood infection)

What are the common drug interactions of Prednisolone and Choline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Blood glucose increased
  2. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  3. Blood potassium increased
  4. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  5. Rash
  6. Swelling face
  7. Bradycardia (abnormally slow heart action)
  8. Oxygen saturation decreased
  9. Pneumomediastinum (air is present in the mediastinum)
  10. Pneumoperitoneum (air or gas in the abdominal (peritoneal) cavity)

50-59:

  1. Diarrhoea
  2. Nausea (feeling of having an urge to vomit)
  3. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  4. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  5. Gastric polyps (abnormal growth of stomach tissue projecting from a mucous membrane)
  6. Gastritis (inflammation of stomach)
  7. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)

60+:

  1. Coma (state of unconsciousness lasting more than six hours)
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Hypotension (abnormally low blood pressure)
  4. Intestinal obstruction
  5. Septic shock (shock due to blood infection)
  6. Tongue necrosis (death of tongue tissue)
  7. White blood cell count decreased
  8. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Drug ineffective

What are the existing conditions these people have? *

  1. Pain: 21 people, 35.00%
  2. Stomatitis (inflammation of mucous membrane of mouth): 12 people, 20.00%
  3. Breast Cancer Metastatic: 12 people, 20.00%
  4. Rashes (redness): 12 people, 20.00%
  5. Oral Herpes (viral infection of mouth): 12 people, 20.00%
  6. Diarrhea: 9 people, 15.00%
  7. High Blood Pressure: 6 people, 10.00%
  8. Muscle Aches (muscle pain): 4 people, 6.67%
  9. Multiple Myeloma (cancer of the plasma cells): 4 people, 6.67%
  10. Atherosclerosis (disorder of the arteries): 4 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Prednisolone and Choline?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prednisolone and Choline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Choline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prednisolone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Choline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on prednisolone and choline (the active ingredients of Prednisolone and Choline, respectively), and Prednisolone and Choline (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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