Prednisolone and Invokana drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prednisolone (prednisolone) and Invokana (canagliflozin). Common drug interactions include diabetic ketoacidosis among females and glomerular filtration rate decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Prednisolone and Invokana. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.

What is Invokana?

Invokana has active ingredients of canagliflozin. It is often used in diabetes. eHealthMe is studying from 29,937 Invokana users. Check the latest studies of Invokana.

On Jul, 15, 2026

32 people who take Prednisolone and Invokana together, and have interactions are studied.

Prednisolone and Invokana drug interactions.

What are the common drug interactions of Prednisolone and Invokana, by gender? *:

female:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Pancreatitis (inflammation of pancreas)
Abdominal discomfort
Drug hypersensitivity
Pain in extremity
Acetonaemia (acetone bodies in the blood)
Blood glucose increased
Blood pressure increased
Chronic kidney disease

male:

Glomerular filtration rate decreased
Benign prostatic hyperplasia (benign enlargement of the prostate)
Injection site haemorrhage (bleeding from injection site)
Injection site pain
Nephrolithiasis (calculi in the kidneys)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis (death of bone)
Renal impairment (severely reduced kidney function)
Tooth loss
Blood glucose increased

What are the common drug interactions of Prednisolone and Invokana, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Blood glucose increased
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Confusional state
Decreased appetite
Drug ineffective
Dyspepsia (indigestion)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

n/a

40-49:

Blood creatinine increased
Bone density decreased
Bone loss
Chronic kidney disease
Glomerular filtration rate decreased
Hip arthroplasty
Nephrolithiasis (calculi in the kidneys)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis (death of bone)
Renal impairment (severely reduced kidney function)

50-59:

Acetonaemia (acetone bodies in the blood)
Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

60+:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Erythema (redness of the skin)
Flatulence (flatus expelled through the anus)
Fungal infection
Glycosylated haemoglobin increased
Headache (pain in head)
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Ketoacidosis (high concentrations of ketone bodies in blood)
Lower respiratory tract infection

What are the existing conditions these people have? *

Type 2 Diabetes: 12 people, 37.50%
Latent Tuberculosis (hidden tuberculosis): 7 people, 21.88%
High Blood Pressure: 5 people, 15.62%
Neuralgia (pain in one or more nerves): 4 people, 12.50%
Indigestion: 4 people, 12.50%
Dyslipidaemia (abnormal amount of lipids): 4 people, 12.50%
Ill-Defined Disorder: 3 people, 9.38%
High Blood Cholesterol: 3 people, 9.38%
Rickets (softening of bones): 2 people, 6.25%
Hiv Infection: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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