Prednisolone and Northera drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Prednisolone (prednisolone) and Northera (droxidopa). Common drug interactions include blood pressure increased among females and pruritus among males.
The phase IV clinical study analyzes what interactions people have when they take Prednisolone and Northera. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Prednisolone?
Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.
What is Northera?
Northera has active ingredients of droxidopa. eHealthMe is studying from 22,874 Northera users. Check the latest studies of Northera.
21 people who take Prednisolone and Northera together, and have interactions are studied.

What are the common drug interactions of Prednisolone and Northera, by gender? *:
female:
- Blood pressure increased
- Asthenia (weakness)
- Cough
- Decreased appetite
- Diarrhoea
- Fatigue (feeling of tiredness)
- Pleural effusion (water on the lungs)
- Pneumonia
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Abdominal pain lower
male:
- Pruritus (severe itching of the skin)
- Death
- Renal disorder (kidney disease)
- Macule (a discoloured spot on the skin)
- Rash
- Headache (pain in head)
- Rash pruritic (redness with itching)
- Back pain
- Blood pressure fluctuation
- Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
What are the common drug interactions of Prednisolone and Northera, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Blood pressure increased
- Dizziness
30-39:
- Abdominal pain lower
- Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
- Pelvic pain
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Ammonia increased
- Depression
- Electrocardiogram qt prolonged
- Genital rash (rash on sex organ)
- Hypertension (high blood pressure)
- Liver disorder (liver diseases)
40-49:
n/a
50-59:
n/a
60+:
- Asthenia (weakness)
- Blood pressure increased
- Death
- Rash
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Drug ineffective
- Headache (pain in head)
- Rash pruritic (redness with itching)
- Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
- Confusional state
What are the existing conditions these people have? *
- Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 14 people, 66.67%
- Neurodegenerative Disorder (progressive loss of structure or function of neurons and death of neuron): 3 people, 14.29%
- Fainting (loss of consciousness and postural tone): 3 people, 14.29%
- Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 3 people, 14.29%
* Approximation only. Some reports may have incomplete information.
Do you take Prednisolone and Northera?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Prednisolone (212,675 reports)
- Northera (22,874 reports)
Browse all drug interactions of Prednisolone and Northera:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Prednisolone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Northera:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Prednisolone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Northera and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Abdullah, D., Mohamed, A. M. F. S., & Liew, A. K. C., "Dentine hypersensitivity-like tooth pain associated with the use of high-dose steroid therapy", Journal of conservative dentistry: JCD, 2018 Jan .
- Abdullah, D., Mohamed, A. M. F. S., & Liew, A. K. C., "Dentine hypersensitivity-like tooth pain associated with the use of high-dose steroid therapy", Journal of conservative dentistry: JCD, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on prednisolone and droxidopa (the active ingredients of Prednisolone and Northera, respectively), and Prednisolone and Northera (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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