Prednisone and A-hydrocort drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prednisone (prednisone) and A-hydrocort (hydrocortisone sodium succinate). Common drug interactions include helicobacter infection among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Prednisone and A-hydrocort. It is created by eHealthMe based on reports of 94 people who take the same drugs from the FDA, and is updated regularly.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

What is A-hydrocort?

A-hydrocort has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 636 A-hydrocort users. Check the latest studies of A-hydrocort.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

94 people who take Prednisone and A-hydrocort together, and have interactions are studied.

Prednisone and A-hydrocort drug interactions.

What are the common drug interactions of Prednisone and A-Hydrocort, by gender? *:

female:

Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Hypersensitivity
Rash
Serum sickness (hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum)
Abdominal distension
Anaemia (lack of blood)
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Cerebral microhaemorrhage (bleeding in brain less than 5 mm in size)
Chest pain

male:

Diarrhoea
Abdominal discomfort
Immune system disorder
Mouth ulceration (mouth ulcers)
Oesophageal candidiasis (fungal infection of oesophagus)
Sinusitis (inflammation of sinus)
Tinnitus (a ringing in the ears)
Ulcer
Asthenia (weakness)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)

What are the common drug interactions of Prednisone and A-Hydrocort, by age (0-1 to 60+)? *:

0-1:

Dyspnoea (difficult or laboured respiration)
Hypertension (high blood pressure)
Pneumonia
Vomiting

2-9:

Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)

10-19:

Serum sickness (hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum)

20-29:

Malaise (a feeling of general discomfort or uneasiness)

30-39:

Asthenia (weakness)
Colitis ulcerative (inflammation of colon with ulcer)
Dizziness
Drug ineffective
Dysarthria (speech disorder)
Haematochezia (passage of stools containing blood)
Hypertension (high blood pressure)
Infection
Influenza like illness
Infusion related reaction

40-49:

Diarrhoea
Rash
Chronic kidney disease
Abdominal discomfort
Alopecia (absence of hair from areas of the body)
Arthropathy
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Discomfort
Drug ineffective
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)

50-59:

Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Lung transplant rejection (failure of lung transplant)
Memory impairment
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Obliterative bronchiolitis (bronchiolar inflammation)
Oedema peripheral (superficial swelling)
Pneumonia
Productive cough
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Respiratory distress (difficulty in breathing)

60+:

Soft tissue haemorrhage (bleeding soft tissue)
Drug ineffective
Cardiomyopathy (weakening of the heart muscle)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Constipation
Crying
Death
Dyspnoea (difficult or laboured respiration)
Ejection fraction decreased (systolic heart failure)
Eructation (release of gas from the digestive tract)

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 9 people, 9.57%
High Blood Pressure: 9 people, 9.57%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 9.57%
Renal Cell Carcinoma (a kidney cancer): 8 people, 8.51%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 7.45%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 7.45%
Stress And Anxiety: 6 people, 6.38%
Nausea (feeling of having an urge to vomit): 6 people, 6.38%
Diabetes: 6 people, 6.38%
Constipation: 6 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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