Prednisone and Azactam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prednisone (prednisone) and Azactam (aztreonam). Common drug interactions include thrombocytopenia among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Prednisone and Azactam. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

What is Azactam?

Azactam has active ingredients of aztreonam. eHealthMe is studying from 1,044 Azactam users. Check the latest studies of Azactam.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

42 people who take Prednisone and Azactam together, and have interactions are studied.

Prednisone and Azactam drug interactions.

What are the common drug interactions of Prednisone and Azactam, by gender? *:

female:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Hypotension (abnormally low blood pressure)
  3. Multi-organ failure (multisystem organ failure)
  4. Renal failure acute (rapid kidney dysfunction)
  5. Septic shock (shock due to blood infection)
  6. Vesical fistula (a fistulous passage from the urinary bladder)
  7. Cardiac arrest
  8. Complications of transplanted kidney
  9. Colitis (inflammation of colon)
  10. Diarrhoea

male:

  1. Drug ineffective
  2. Encephalopathy (functioning of the brain is affected by some agent or condition)
  3. Loss of consciousness
  4. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  5. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
  6. Septic shock (shock due to blood infection)
  7. Bacterial sepsis
  8. Bone marrow failure
  9. Coagulopathy (blood's ability to clot is impaired)
  10. Diabetes mellitus inadequate control

What are the common drug interactions of Prednisone and Azactam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Injury
  3. Pain

20-29:

  1. Respiratory failure (inadequate gas exchange by the respiratory system)

30-39:

  1. Cardiac arrest
  2. Drug administration error
  3. Haemolytic anaemia (anaemia due to haemolysis)
  4. Hyperkalaemia (damage to or disease of the kidney)
  5. Thrombocytopenia (decrease of platelets in blood)
  6. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
  7. Liver injury
  8. Renal failure acute (rapid kidney dysfunction)
  9. Hepatocellular injury (liver injury)
  10. Rash

40-49:

  1. Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
  2. Dyspnoea (difficult or laboured respiration)
  3. Injury
  4. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  5. Pain
  6. Pulmonary embolism (blockage of the main artery of the lung)

50-59:

  1. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  2. Septic shock (shock due to blood infection)
  3. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
  4. Renal failure (kidney dysfunction)
  5. Bacterial sepsis
  6. Bone marrow failure
  7. Coagulopathy (blood's ability to clot is impaired)
  8. Diabetes mellitus inadequate control
  9. Hepatocellular injury (liver injury)
  10. Chronic kidney disease

60+:

  1. Vesical fistula (a fistulous passage from the urinary bladder)
  2. Drug ineffective
  3. Hypokalaemia (low potassium)
  4. Hypotension (abnormally low blood pressure)
  5. Infection
  6. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  7. Multi-organ failure (multisystem organ failure)
  8. Oral candidiasis (fungal infection of mouth)
  9. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  10. Pyrexia (fever)

What are the existing conditions these people have? *

  1. Diabetes: 5 people, 11.90%
  2. Cytomegalovirus Infection: 5 people, 11.90%
  3. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 4 people, 9.52%
  4. Pneumonia: 4 people, 9.52%
  5. Pain: 4 people, 9.52%
  6. Optic Ischaemic Neuropathy (optic nerve damage due to lack of blood supply): 3 people, 7.14%
  7. Nausea (feeling of having an urge to vomit): 3 people, 7.14%
  8. Mucosal Inflammation (infection of mucous membrane): 3 people, 7.14%
  9. Leukaemia (blood or bone marrow cancer): 3 people, 7.14%
  10. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prednisone and Azactam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prednisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Azactam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prednisone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azactam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on prednisone and aztreonam (the active ingredients of Prednisone and Azactam, respectively), and Prednisone and Azactam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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