Prednisone and Ozurdex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prednisone (prednisone) and Ozurdex (dexamethasone). Common drug interactions include vision blurred among females and intraocular pressure increased among males.

The phase IV clinical study analyzes what interactions people have when they take Prednisone and Ozurdex. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

What is Ozurdex?

Ozurdex has active ingredients of dexamethasone. eHealthMe is studying from 2,497 Ozurdex users. Check the latest studies of Ozurdex.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 27, 2026

68 people who take Prednisone and Ozurdex together, and have interactions are studied.

Prednisone and Ozurdex drug interactions.

What are the common drug interactions of Prednisone and Ozurdex, by gender? *:

female:

  1. Vision blurred
  2. Eye abscess
  3. Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
  4. Ocular hyperaemia (an abnormally large amount of blood in eye)
  5. Rebound effect (take-back effect)
  6. Blindness
  7. Cystoid macular oedema (fluid accumulation after cataract surgery)
  8. Visual impairment
  9. Conjunctival haemorrhage (bleeding underneath the conjunctiva)
  10. Drug ineffective

male:

  1. Intraocular pressure increased
  2. Drug ineffective
  3. Cataract (clouding of the lens inside the eye)
  4. Cataract subcapsular (cataracts that affect the back of the lens)
  5. Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
  6. Disease progression
  7. Nasopharyngitis (inflammation of the nasopharynx)
  8. Macular fibrosis (a thin sheet of scar tissue forms on top of the macula, in response to damage or injury)
  9. Ocular hypertension (intraocular pressure higher than normal)
  10. Retinal haemorrhage (bleeding from retina)

What are the common drug interactions of Prednisone and Ozurdex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Conjunctival haemorrhage (bleeding underneath the conjunctiva)
  2. Eye pain
  3. Intraocular pressure decreased
  4. Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
  5. Ocular hypertension (intraocular pressure higher than normal)
  6. Vision blurred
  7. Visual acuity reduced (reduced clearness of vision)
  8. Vitreous opacities (vitreous opacities generally develop as aging changes within the eye)
  9. Cataract subcapsular (cataracts that affect the back of the lens)
  10. Visual impairment

20-29:

n/a

30-39:

  1. Choroiditis (infection of vascular layer of eye)
  2. Drug ineffective
  3. Endophthalmitis (inflammation of the internal coats of the eye)
  4. Eye pain
  5. Intraocular pressure increased
  6. Uveitis (inflammation of the uvea)
  7. Visual acuity reduced (reduced clearness of vision)
  8. Chondritis (inflammation of cartilage)
  9. Visual impairment
  10. Vision blurred

40-49:

  1. Intraocular pressure increased
  2. Visual impairment
  3. Cataract subcapsular (cataracts that affect the back of the lens)
  4. Macular fibrosis (a thin sheet of scar tissue forms on top of the macula, in response to damage or injury)
  5. Eye infection toxoplasmal (a germ called toxoplasma can cause infection within the eye)
  6. Retinal ischaemia (lack of blood supply to retina)

50-59:

  1. Cataract (clouding of the lens inside the eye)
  2. Intraocular pressure increased
  3. Blindness
  4. Corneal oedema (corneal swelling)
  5. Device dislocation
  6. Cataract traumatic (cataract by trauma or injury)
  7. Complication of device insertion

60+:

  1. Eye abscess
  2. Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
  3. Impaired healing
  4. Abnormal behaviour
  5. Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
  6. Aggression
  7. Anxiety
  8. Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
  9. Conjunctivitis allergic (inflammation of the conjunctiva due to allergy)
  10. Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

  1. Uveitis (inflammation of the uvea): 30 people, 44.12%
  2. Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 15 people, 22.06%
  3. Endophthalmitis (inflammation of the internal coats of the eye): 10 people, 14.71%
  4. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 9 people, 13.24%
  5. Iridocyclitis (inflammation of the iris and ciliary body of the eye): 9 people, 13.24%
  6. Idiopathic Pulmonary Fibrosis (chronic lung disease): 8 people, 11.76%
  7. Cystoid Macular Oedema (fluid accumulation after cataract surgery): 7 people, 10.29%
  8. Whipple's Disease (infection with a bacteria called tropheryma whippelii): 5 people, 7.35%
  9. Retinal Vasculitis (a sight-threatening inflammatory eye condition that involves the retinal vessels): 4 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prednisone and Ozurdex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prednisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ozurdex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prednisone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ozurdex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on prednisone and dexamethasone (the active ingredients of Prednisone and Ozurdex, respectively), and Prednisone and Ozurdex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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