Prednisone and Targiniq drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prednisone (prednisone) and Targiniq (naloxone hydrochloride; oxycodone hydrochloride). Common drug interactions include malaise among females and cytokine release syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Prednisone and Targiniq. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

What is Targiniq?

Targiniq has active ingredients of naloxone hydrochloride; oxycodone hydrochloride. eHealthMe is studying from 580 Targiniq users. Check the latest studies of Targiniq.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

21 people who take Prednisone and Targiniq together, and have interactions are studied.

Prednisone and Targiniq drug interactions.

What are the common drug interactions of Prednisone and Targiniq, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Peripheral motor neuropathy (muscles in the body become progressively weaker over months to years)

male:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Hypotension (abnormally low blood pressure)
Osteitis (a general term for inflammation of bone)
Osteonecrosis of jaw (death of bone of jaw)
Hypoxia (low oxygen in tissues)
Respiratory failure (inadequate gas exchange by the respiratory system)
Femur fracture
Pyrexia (fever)
Device related infection
Febrile neutropenia (fever with reduced white blood cells)

What are the common drug interactions of Prednisone and Targiniq, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Femur fracture
Pyrexia (fever)
Device related infection
Febrile neutropenia (fever with reduced white blood cells)

50-59:

Malaise (a feeling of general discomfort or uneasiness)
Peripheral motor neuropathy (muscles in the body become progressively weaker over months to years)

60+:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Hypotension (abnormally low blood pressure)
Hypoxia (low oxygen in tissues)
Respiratory failure (inadequate gas exchange by the respiratory system)
Spondylitis (an inflammation of the vertebra with spinal cord involvement)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Osteitis (a general term for inflammation of bone)
Osteonecrosis of jaw (death of bone of jaw)

What are the existing conditions these people have? *

Diffuse Large B-Cell Lymphoma Stage Iv (cancer of b cells, a type of white blood cell-stage iv): 9 people, 42.86%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 7 people, 33.33%
Burkitt Lymphoma (cancer of the lymphatic system): 5 people, 23.81%
Prostate Cancer Metastatic: 2 people, 9.52%
Fever: 2 people, 9.52%
Femur Fracture: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Prednisone and Targiniq?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously