Prednisone and Trulance drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Prednisone (prednisone) and Trulance (plecanatide). Common drug interactions include adverse drug reaction among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people have when they take Prednisone and Trulance. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.
What is Prednisone?
Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.
What is Trulance?
Trulance has active ingredients of plecanatide. eHealthMe is studying from 1,746 Trulance users. Check the latest studies of Trulance.
73 people who take Prednisone and Trulance together, and have interactions are studied.

What are the common drug interactions of Prednisone and Trulance, by gender? *:
female:
- Adverse drug reaction
- Appendicitis (inflammation of the appendix)
- Arthralgia (joint pain)
- Asthma exercise induced
- Back disorder
- Bladder cyst
- Bowel movement irregularity
- Breast mass
- Bronchial secretion retention
- Chapped lips (cracking, fissuring, and peeling of the skin f lip)
male:
- Diarrhoea
- Pain
- Faeces discoloured
- Gastric disorder (disease of stomach)
- Thirst
- Arthralgia (joint pain)
- Clumsiness (a lack of coordination or elegance)
- Drug ineffective
- Fall
- Injection site discharge
What are the common drug interactions of Prednisone and Trulance, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Respiratory distress (difficulty in breathing)
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Wheezing (a high-pitched whistling sound made while you breath)
40-49:
- Abdominal distension
- Diarrhoea
- Gastric disorder (disease of stomach)
- Thirst
50-59:
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Skin cancer
- Surgery
- Oral herpes (viral infection of mouth)
- Pain
- Sinus disorder (disease of sinus)
- Abdominal discomfort
- Breast mass
- Bronchial secretion retention
- Clumsiness (a lack of coordination or elegance)
60+:
- Chronic kidney disease
- Diarrhoea
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
- Chest pain
- Confusional state
- Cough
- Dyspnoea (difficult or laboured respiration)
- Erythema (redness of the skin)
- Fatigue (feeling of tiredness)
What are the existing conditions these people have? *
- Constipation: 11 people, 15.07%
- Asthma: 9 people, 12.33%
- Immunodeficiency Common Variable: 8 people, 10.96%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 9.59%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 6.85%
- Stress And Anxiety: 4 people, 5.48%
- Headache (pain in head): 4 people, 5.48%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 5.48%
* Approximation only. Some reports may have incomplete information.
Do you take Prednisone and Trulance?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Prednisone (636,827 reports)
- Trulance (1,746 reports)
Browse all drug interactions of Prednisone and Trulance:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Prednisone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Trulance:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Prednisone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Trulance and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on prednisone and plecanatide (the active ingredients of Prednisone and Trulance, respectively), and Prednisone and Trulance (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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