Prednisone and Tykerb drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prednisone (prednisone) and Tykerb (lapatinib ditosylate). Common drug interactions include diarrhoea among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Prednisone and Tykerb. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

What is Tykerb?

Tykerb has active ingredients of lapatinib ditosylate. It is often used in breast cancer. eHealthMe is studying from 12,231 Tykerb users. Check the latest studies of Tykerb.

On Jul, 18, 2026

72 people who take Prednisone and Tykerb together, and have interactions are studied.

Prednisone and Tykerb drug interactions.

What are the common drug interactions of Prednisone and Tykerb, by gender? *:

female:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Vomiting
Thrombocytopenia (decrease of platelets in blood)
Death
Fatigue (feeling of tiredness)
Dehydration (dryness resulting from the removal of water)
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Rash
Neoplasm progression (growth of tumour)

male:

Pneumonia
Anxiety
Physical disability
Back pain
Constipation
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Metastases to lung (cancer spreads to lung)
Metastases to spine (cancer spreads to spine)

What are the common drug interactions of Prednisone and Tykerb, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anxiety
Dysphagia (a condition in which swallowing is difficult or painful)
Injury
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Osteonecrosis of jaw (death of bone of jaw)
Otitis externa (external ear infection)
Pain
Pneumonia
Vomiting

40-49:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Vomiting
Abdominal pain upper
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Adrenal mass
Anxiety
Aortic valve incompetence
Aphagia (inability or refusal to swallow)
Arthralgia (joint pain)

50-59:

Vomiting
Abdominal pain upper
Anxiety
Arthralgia (joint pain)
Constipation
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Fatigue (feeling of tiredness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)

60+:

Diarrhoea
Vomiting
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood bilirubin increased
Cardiac failure
Epistaxis (bleed from the nose)
Hypertrophic cardiomyopathy (a condition in which the heart muscle becomes abnormally thick)
Vitamin d deficiency
Dry skin

What are the existing conditions these people have? *

Breast Cancer Metastatic: 19 people, 26.39%
Hypertensive Crisis: 6 people, 8.33%
High Blood Pressure: 6 people, 8.33%
Rickets (softening of bones): 5 people, 6.94%
Diabetes: 5 people, 6.94%
Breast Cancer Female: 5 people, 6.94%
Thyroid Diseases: 4 people, 5.56%
Stress And Anxiety: 4 people, 5.56%
Insomnia (sleeplessness): 4 people, 5.56%
High Blood Cholesterol: 4 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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