Pregabalin and Folate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Pregabalin (pregabalin) and Folate (folic acid). Common drug interactions include decreased appetite among females and ageusia among males.
The phase IV clinical study analyzes what interactions people have when they take Pregabalin and Folate. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.
What is Pregabalin?
Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,070 Pregabalin users. Check the latest studies of Pregabalin.
What is Folate?
Folate has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 6,546 Folate users. Check the latest studies of Folate.
44 people who take Pregabalin and Folate together, and have interactions are studied.

What are the common drug interactions of Pregabalin and Folate, by gender? *:
female:
- Decreased appetite
- Delirium (wild excitement)
- Depressed level of consciousness
- Depressed mood
- Dizziness
- Drug ineffective
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Ear pruritus (pruritus or itching is ""the unpleasant skin sensation that frequently provokes scratching"" in ear)
- Energy increased
- Eye disorder
male:
- Ageusia (loss of taste functions of the tongue)
- Dry mouth
- Pain of skin
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Thirst
- Urge incontinence (urinary incontinence)
- Visual impairment
- Weight increased
- Chronic kidney disease
- Pneumonia
What are the common drug interactions of Pregabalin and Folate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Dyspnoea (difficult or laboured respiration)
- Energy increased
- Eye disorder
- Fatigue (feeling of tiredness)
- Flushing (the warm, red condition of human skin)
- Heart rate increased
- Migraine (headache)
- Optic neuritis (optic nerve inflammation)
40-49:
- Migraine (headache)
- Rash
50-59:
- Depressed mood
- Dizziness
- Facial paresis (weakness in facial muscle movement)
- Headache (pain in head)
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
- Hepatic failure (liver failure)
- Hypoaesthesia (reduced sense of touch or sensation)
- Meningioma (a diverse set of tumours arising from the meninges)
- Migraine with aura (headache with vision weakness)
- Mitral valve incompetence (inefficient heart valve)
60+:
- Fall
- Pneumonia
- Blood cholesterol increased
- Bursa injury
- Cardiac arrest
- Cellulitis (infection under the skin)
- Chronic inflammatory demyelinating polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord)
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Constipation
- Contusion (a type of hematoma of tissue in which capillaries)
What are the existing conditions these people have? *
- Pain: 9 people, 20.45%
- Migraine (headache): 9 people, 20.45%
- Nausea (feeling of having an urge to vomit): 7 people, 15.91%
- Ovarian Cancer (cancer of ovary): 5 people, 11.36%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 11.36%
- Constipation: 5 people, 11.36%
- Headache (pain in head): 4 people, 9.09%
- Depression: 4 people, 9.09%
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 6.82%
- Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 3 people, 6.82%
* Approximation only. Some reports may have incomplete information.
Do you take Pregabalin and Folate?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Pregabalin (74,070 reports)
- Folate (6,546 reports)
Browse all drug interactions of Pregabalin and Folate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Pregabalin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Folate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pregabalin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Folate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on pregabalin and folic acid (the active ingredients of Pregabalin and Folate, respectively), and Pregabalin and Folate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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