Premarin and Alcohol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Premarin (estrogens, conjugated) and Alcohol (alcohol). Common drug interactions include visual acuity reduced among females and alcohol interaction among males.

The phase IV clinical study analyzes what interactions people have when they take Premarin and Alcohol. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

What is Alcohol?

Alcohol has active ingredients of alcohol. It is often used in stress and anxiety. eHealthMe is studying from 23,388 Alcohol users. Check the latest studies of Alcohol.

On Aug, 03, 2026

46 people who take Premarin and Alcohol together, and have interactions are studied.

What are the common drug interactions of Premarin and Alcohol, by gender? *:

female:

Visual acuity reduced (reduced clearness of vision)
Back pain
Bone pain
Confusional state
Hypotension (abnormally low blood pressure)
Osteomyelitis (infection of bone)
Pain
Pyrexia (fever)
Vomiting
Abscess (pus)

male:

Alcohol interaction
Alcohol withdrawal syndrome
Hot flush (sudden feelings of heat)
Hyperhidrosis (abnormally increased sweating)

What are the common drug interactions of Premarin and Alcohol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abscess (pus)
Anaemia of chronic disease
Arrhythmia supraventricular (irregular heartbeat supraventricular origin)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Back pain
Blood creatinine increased
Blood glucose increased
Blood pressure fluctuation
Blood urea increased

20-29:

n/a

30-39:

Abdominal pain
Abdominal pain upper
Adjustment disorder with depressed mood
Arrhythmia (irregular heartbeat)
Caecitis (inflammation of the cecum)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Chest discomfort
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Depressed mood
Diarrhoea

40-49:

Abdominal pain upper
Arthralgia (joint pain)
Back pain
Blood glucose increased
Bone pain
Chronic kidney disease
Cough
Depression
Drug ineffective
Dyspepsia (indigestion)

50-59:

Sleep talking (talking during sleeping)
Somnambulism (sleep walking)
Transient global amnesia (a temporary short-term memory loss)
Confusional state
Feeling drunk
Hangover
Hypertension (high blood pressure)
Hypoaesthesia (reduced sense of touch or sensation)
Memory impairment
Muscle spasms (muscle contraction)

60+:

Dysphagia (a condition in which swallowing is difficult or painful)
Constipation
Blood urea increased
Bone disorder
Bone pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Cataract (clouding of the lens inside the eye)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 41.30%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 19 people, 41.30%
Drowsiness: 18 people, 39.13%
Pain: 7 people, 15.22%
Sleep Disorder: 6 people, 13.04%
Neuropathy Peripheral (surface nerve damage): 5 people, 10.87%
Nerve Block (the interruption of signals travelling along a nerve): 4 people, 8.70%
Neck Pain: 4 people, 8.70%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 4 people, 8.70%
Muscle Spasms (muscle contraction): 4 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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