Prevacid and Actifed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prevacid (lansoprazole) and Actifed (pseudoephedrine hydrochloride; triprolidine hydrochloride). Common drug interactions include pain among females and myocardial ischaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Prevacid and Actifed. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Prevacid?

Prevacid has active ingredients of lansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 130,714 Prevacid users. Check the latest studies of Prevacid.

What is Actifed?

Actifed has active ingredients of pseudoephedrine hydrochloride; triprolidine hydrochloride. It is often used in allergies. eHealthMe is studying from 1,091 Actifed users. Check the latest studies of Actifed.

On Jul, 15, 2026

77 people who take Prevacid and Actifed together, and have interactions are studied.

What are the common drug interactions of Prevacid and Actifed, by gender? *:

female:

Pain
Abdominal discomfort
Back pain
Hypoaesthesia (reduced sense of touch or sensation)
Abdominal pain
Anaphylactic reaction (serious allergic reaction)
Neck pain
Erythema (redness of the skin)
Myalgia (muscle pain)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)

male:

Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Abdominal pain
Blood glucose increased
Blood potassium increased
Blood sodium decreased
Blood triglycerides increased
Blood urea increased
Bradycardia (abnormally slow heart action)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)

What are the common drug interactions of Prevacid and Actifed, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Back pain
Pneumonia

40-49:

Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Dyspnoea (difficult or laboured respiration)
Joint swelling
Injury
Lower respiratory tract infection
Pain
Sinusitis (inflammation of sinus)
Maternal exposure during pregnancy (use of substance during pregnancy)
Peripheral swelling
Alopecia (absence of hair from areas of the body)

50-59:

Blood albumin decreased
Blood alkaline phosphatase nos increased
Blood bilirubin increased
Blood chloride decreased
Blood potassium increased
Blood sodium decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic obstructive airways disease
Cirrhosis alcoholic (chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue caused by alcoholism)
Confusion

60+:

Anaphylactic reaction (serious allergic reaction)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea
Drug hypersensitivity
Dysphagia (a condition in which swallowing is difficult or painful)
Dysphoria (generalized dissatisfaction with life)
Dyspnoea (difficult or laboured respiration)
Ear pain

What are the existing conditions these people have? *

Dizziness: 42 people, 54.55%
Pain: 19 people, 24.68%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 16 people, 20.78%
Stress And Anxiety: 12 people, 15.58%
Ankylosing Spondylitis (type of arthritis affecting the spine): 10 people, 12.99%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 10 people, 12.99%
Psoriasis (immune-mediated disease that affects the skin): 10 people, 12.99%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 10 people, 12.99%
Fever: 8 people, 10.39%
Migraine (headache): 7 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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