Prevymis and Ursodeoxycholic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prevymis (letermovir) and Ursodeoxycholic acid (ursodiol). Common drug interactions include febrile neutropenia among females and acute graft versus host disease in skin among males.

The phase IV clinical study analyzes what interactions people have when they take Prevymis and Ursodeoxycholic acid. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Prevymis?

Prevymis has active ingredients of letermovir. eHealthMe is studying from 1,328 Prevymis users. Check the latest studies of Prevymis.

What is Ursodeoxycholic acid?

Ursodeoxycholic acid has active ingredients of ursodiol. It is often used in biliary cirrhosis primary. eHealthMe is studying from 7,528 Ursodeoxycholic acid users. Check the latest studies of Ursodeoxycholic acid.

On Aug, 09, 2026

21 people who take Prevymis and Ursodeoxycholic acid together, and have interactions are studied.

Prevymis and Ursodeoxycholic acid drug interactions.

What are the common drug interactions of Prevymis and Ursodeoxycholic Acid, by gender? *:

female:

Febrile neutropenia (fever with reduced white blood cells)
Cardiac arrest
Cardiac tamponade (fluid accumulates in heart covering)
Cardiomyopathy (weakening of the heart muscle)
Cystitis (inflammation of the wall of the bladder)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Irritability
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)

male:

Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
Cytomegalovirus infection
Coma hepatic (accumulation in the bloodstream of toxic substances that are normally removed by the liver leads coma)
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Drug eruption (adverse drug reaction of the skin)
Engraftment syndrome (inflammatory condition during neutrophil recovery after hematopoietic stem cell transplantation)
Epstein-barr virus associated lymphoproliferative disorder (lymphocytes are produced in excessive quantities associated with epstein-barr virus)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Graft versus host disease in skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)

What are the common drug interactions of Prevymis and Ursodeoxycholic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Coma hepatic (accumulation in the bloodstream of toxic substances that are normally removed by the liver leads coma)
Engraftment syndrome (inflammatory condition during neutrophil recovery after hematopoietic stem cell transplantation)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hepatic failure (liver failure)
Platelet count decreased
Venoocclusive liver disease (small veins in the liver are obstructed)

20-29:

Oesophagitis (inflammation of oesophagus)
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Febrile neutropenia (fever with reduced white blood cells)
Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
Cytomegalovirus infection
Cytomegalovirus test positive

30-39:

Renal impairment (severely reduced kidney function)
Thrombocytopenia (decrease of platelets in blood)
Bicytopenia (two parameters from the full blood count are low, the term bicytopenia can be used)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

40-49:

Adverse event
Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
Cardiac arrest
Cardiac tamponade (fluid accumulates in heart covering)
Cardiomyopathy (weakening of the heart muscle)
Cystitis (inflammation of the wall of the bladder)
Cytomegalovirus infection
Febrile neutropenia (fever with reduced white blood cells)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Irritability

50-59:

Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Platelet count decreased
Sensation of foreign body
Anaemia (lack of blood)
Febrile neutropenia (fever with reduced white blood cells)
Epstein-barr virus associated lymphoproliferative disorder (lymphocytes are produced in excessive quantities associated with epstein-barr virus)
Graft versus host disease in skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin)
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Lactic acidosis (low ph in body tissues)
Pericardial effusion (fluid around the heart)
Pericardial haemorrhage (bleeding into the heart)

What are the existing conditions these people have? *

Hepatic Function Abnormal: 3 people, 14.29%
Febrile Neutropenia (fever with reduced white blood cells): 3 people, 14.29%
Acute Myeloid Leukaemia Recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent): 3 people, 14.29%
Venoocclusive Liver Disease (small veins in the liver are obstructed): 2 people, 9.52%
Stress Gastritis (swelling (inflammation) and weakening of the stomach lining that occurs during a serious illness): 2 people, 9.52%
Sepsis (a severe blood infection that can lead to organ failure and death): 2 people, 9.52%
Oedema Peripheral (superficial swelling): 2 people, 9.52%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 9.52%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 9.52%
Gastric Ulcer (stomach ulcer): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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