Promethazine and Kalbitor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promethazine (promethazine hydrochloride) and Kalbitor (ecallantide). Common drug interactions include hereditary angioedema among females and hereditary angioedema among males.

The phase IV clinical study analyzes what interactions people have when they take Promethazine and Kalbitor. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Promethazine?

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 32,300 Promethazine users. Check the latest studies of Promethazine.

What is Kalbitor?

Kalbitor has active ingredients of ecallantide. eHealthMe is studying from 2,079 Kalbitor users. Check the latest studies of Kalbitor.

On Aug, 09, 2026

23 people who take Promethazine and Kalbitor together, and have interactions are studied.

Promethazine and Kalbitor drug interactions.

What are the common drug interactions of Promethazine and Kalbitor, by gender? *:

female:

Hereditary angioedema (recurrent episodes of severe swelling)
Headache (pain in head)
Chest injury
Drug ineffective
Fall
Laryngeal oedema (swelling of larynx)
Neuropathy peripheral (surface nerve damage)
Infusion related reaction
Stress
Weight decreased

male:

Hereditary angioedema (recurrent episodes of severe swelling)
Influenza
Hyperhidrosis (abnormally increased sweating)
Nasopharyngitis (inflammation of the nasopharynx)
Pain
Pain in extremity
Abdominal pain
Angioedema (rapid swelling of the dermis)
Asthma
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the common drug interactions of Promethazine and Kalbitor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Hereditary angioedema (recurrent episodes of severe swelling)
Influenza
Pelvic fluid collection

20-29:

Hereditary angioedema (recurrent episodes of severe swelling)
Pregnancy
Dehydration (dryness resulting from the removal of water)
Hyperemesis gravidarum (a condition characterized by severe nausea, vomiting, weight loss, and electrolyte disturbance)
Maternal exposure during pregnancy (use of substance during pregnancy)

30-39:

Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Blood cholesterol decreased
Haemoglobin decreased
Hereditary angioedema (recurrent episodes of severe swelling)
Abdominal discomfort
Abdominal distension
Drug ineffective
Feeding disorder (when children refuse to eat certain food groups)
Pain

40-49:

Hereditary angioedema (recurrent episodes of severe swelling)
Chills (felling of cold)
Hyperhidrosis (abnormally increased sweating)
Malaise (a feeling of general discomfort or uneasiness)
Nasopharyngitis (inflammation of the nasopharynx)
Pain in extremity
Liposarcoma (a cancer tumour that arises in fat cells in deep soft tissue)
Post procedural infection

50-59:

Pneumonia

60+:

Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Headache (pain in head)
Hereditary angioedema (recurrent episodes of severe swelling)
Oxygen saturation decreased
Swollen tongue (swelling of tongue)
Cough
Malaise (a feeling of general discomfort or uneasiness)
Pneumonia
Pyrexia (fever)

What are the existing conditions these people have? *

Hereditary Angioedema (recurrent episodes of severe swelling): 19 people, 82.61%
Immune System Disorder: 6 people, 26.09%
Stress And Anxiety: 2 people, 8.70%
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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