Prezcobix and Dilaudid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prezcobix (cobicistat; darunavir ethanolate) and Dilaudid (hydromorphone hydrochloride). Common drug interactions include fatigue among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Prezcobix and Dilaudid. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Prezcobix?

Prezcobix has active ingredients of cobicistat; darunavir ethanolate. eHealthMe is studying from 2,113 Prezcobix users. Check the latest studies of Prezcobix.

What is Dilaudid?

Dilaudid has active ingredients of hydromorphone hydrochloride. It is often used in pain. eHealthMe is studying from 96,466 Dilaudid users. Check the latest studies of Dilaudid.

On Jul, 19, 2026

16 people who take Prezcobix and Dilaudid together, and have interactions are studied.

Prezcobix and Dilaudid drug interactions.

What are the common drug interactions of Prezcobix and Dilaudid, by gender? *:

female:

Fatigue (feeling of tiredness)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Cellulitis (infection under the skin)
Dizziness
Drug ineffective
Emotional distress
Euphoric mood (excessively happy but may become angry or irritable)
Faeces discoloured
Headache (pain in head)

male:

Renal failure (kidney dysfunction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Impaired work ability
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Nephrolithiasis (calculi in the kidneys)
Renal transplant
Tooth loss

What are the common drug interactions of Prezcobix and Dilaudid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hand fracture
Rib fracture
Renal failure (kidney dysfunction)
Bone density decreased
Foot fracture
Multiple fractures
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Osteopenia (a condition where bone mineral density is lower than normal)
Renal impairment (severely reduced kidney function)
Gait disturbance

40-49:

Anxiety
Emotional distress
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Decreased activity
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Impaired work ability
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Nephrolithiasis (calculi in the kidneys)

50-59:

Cellulitis (infection under the skin)
Dizziness
Faeces discoloured
Fatigue (feeling of tiredness)
Localised infection (infection at the single location)
Ocular icterus (presence of jaundice seen in the sclera of the eye)
Poor quality sleep
Yellow skin

60+:

n/a

What are the existing conditions these people have? *

Hiv Infection: 14 people, 87.50%
Procedural Pain: 4 people, 25.00%
Infection: 4 people, 25.00%
High Blood Pressure: 4 people, 25.00%
High Blood Cholesterol: 4 people, 25.00%
Diabetes: 4 people, 25.00%
Hepatitis B: 3 people, 18.75%
Peripheral Swelling: 2 people, 12.50%
Hepatitis C: 2 people, 12.50%
Sinusitis (inflammation of sinus): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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