Prezista and Narcan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prezista (darunavir ethanolate) and Narcan (naloxone hydrochloride). Common drug interactions include renal failure among females and bone density decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Prezista and Narcan. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Prezista?

Prezista has active ingredients of darunavir ethanolate. It is often used in hiv infection. eHealthMe is studying from 12,363 Prezista users. Check the latest studies of Prezista.

What is Narcan?

Narcan has active ingredients of naloxone hydrochloride. eHealthMe is studying from 3,687 Narcan users. Check the latest studies of Narcan.

On Jul, 06, 2026

19 people who take Prezista and Narcan together, and have interactions are studied.

What are the common drug interactions of Prezista and Narcan, by gender? *:

female:

Renal failure (kidney dysfunction)
Chronic kidney disease
Emotional distress
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Pneumonia
Renal impairment (severely reduced kidney function)
Anaemia (lack of blood)
Back pain

male:

Bone density decreased
Rib fracture
Foot fracture
Gait disturbance
Multiple fractures
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Osteoporosis (bones weak and more likely to break)
Renal failure (kidney dysfunction)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Osteonecrosis (death of bone)

What are the common drug interactions of Prezista and Narcan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hand fracture
Rib fracture
Bone density decreased
Foot fracture
Multiple fractures
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Osteopenia (a condition where bone mineral density is lower than normal)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Gait disturbance

40-49:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Osteonecrosis (death of bone)
Renal impairment (severely reduced kidney function)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Ankle fracture
Bone density decreased

50-59:

Chronic kidney disease
Emotional distress
Back pain
Depression
Drug resistance (reduction in effectiveness of a drug)
Dyspnoea (difficult or laboured respiration)
Gait disturbance
Glomerulosclerosis (a hardening of the glomerulus in the kidney)
Incontinence (lack of moderation or self-control)
Multiple fractures

60+:

n/a

What are the existing conditions these people have? *

Asthma: 4 people, 21.05%
Inflammation: 3 people, 15.79%
Bacterial Infection: 3 people, 15.79%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.79%
Hepatitis B: 3 people, 15.79%
Quit Smoking: 3 people, 15.79%
Hypersensitivity: 3 people, 15.79%
Viral Infection: 3 people, 15.79%
Menopause (end of monthly cycles in women): 3 people, 15.79%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 15.79%

* Approximation only. Some reports may have incomplete information.

Do you take Prezista and Narcan?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously