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Prilosec and Nac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prilosec (omeprazole) and Nac (n - acetyl cysteine). Common drug interactions include sinusitis among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Prilosec and Nac. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.

What is Nac?

Nac has active ingredients of n - acetyl cysteine. eHealthMe is studying from 855 Nac users. Check the latest studies of Nac.

On Jul, 27, 2026

24 people who take Prilosec and Nac together, and have interactions are studied.

Prilosec and Nac drug interactions.

What are the common drug interactions of Prilosec and Nac, by gender? *:

female:

  1. Sinusitis (inflammation of sinus)
  2. Headache (pain in head)
  3. Ear infection
  4. Respiratory tract infection
  5. Infusion related reaction
  6. Infection
  7. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
  8. Weight decreased
  9. Chest pain
  10. Chills (felling of cold)

male:

  1. Nausea (feeling of having an urge to vomit)
  2. Decreased appetite
  3. Blood glucose increased
  4. Diarrhoea
  5. Fatigue (feeling of tiredness)
  6. Gastric disorder (disease of stomach)
  7. Glycosylated haemoglobin increased
  8. Headache (pain in head)
  9. Hypoaesthesia (reduced sense of touch or sensation)
  10. Idiopathic pulmonary fibrosis (chronic lung disease)

What are the common drug interactions of Prilosec and Nac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Sinusitis (inflammation of sinus)
  2. Headache (pain in head)
  3. Arthropod sting (arthropod bite)
  4. Chest pain
  5. Decreased appetite
  6. Dyspnoea (difficult or laboured respiration)
  7. Fall
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Multiple allergies (allergy to multiple agents)
  10. Paranasal sinus hypersecretion

What are the existing conditions these people have? *

  1. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 5 people, 20.83%
  2. Pain: 3 people, 12.50%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 12.50%
  4. Herpes Virus Infection: 2 people, 8.33%
  5. Bacterial Infection: 2 people, 8.33%
  6. Blood Pressure Abnormal: 2 people, 8.33%
  7. Bone Disorder: 2 people, 8.33%
  8. Diabetes: 2 people, 8.33%
  9. Eye Disorder: 2 people, 8.33%
  10. Gastric Disorder (disease of stomach): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Prilosec and Nac?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prilosec and Nac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prilosec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole and n - acetyl cysteine (the active ingredients of Prilosec and Nac, respectively), and Prilosec and Nac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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