Primidone and Dexedrine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Primidone (primidone) and Dexedrine (dextroamphetamine sulfate). Common drug interactions include irritable bowel syndrome among females and neuropathy peripheral among males.
The phase IV clinical study analyzes what interactions people have when they take Primidone and Dexedrine. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Primidone?
Primidone has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 10,474 Primidone users. Check the latest studies of Primidone.
What is Dexedrine?
Dexedrine has active ingredients of dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 4,735 Dexedrine users. Check the latest studies of Dexedrine.
22 people who take Primidone and Dexedrine together, and have interactions are studied.

What are the common drug interactions of Primidone and Dexedrine, by gender? *:
female:
- Irritable bowel syndrome
- Panic disorder
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Urine bilirubin increased
- Dehydration (dryness resulting from the removal of water)
- Hypertension (high blood pressure)
- Death
- Fall
- Limb injury
- Migraine (headache)
male:
- Neuropathy peripheral (surface nerve damage)
- Constipation
- Fatigue (feeling of tiredness)
- Influenza
- Prostate cancer
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Therapeutic response unexpected
What are the common drug interactions of Primidone and Dexedrine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Fall
- Limb injury
- Influenza
- Prostate cancer
- Surgery
- Therapeutic response unexpected
- Migraine (headache)
- Neuropathy peripheral (surface nerve damage)
- Peroneal nerve palsy
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
60+:
n/a
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 22 people, 100.00%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 16 people, 72.73%
- Drowsiness: 2 people, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Primidone and Dexedrine?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Primidone and Dexedrine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Primidone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Dexedrine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Primidone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dexedrine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on primidone and dextroamphetamine sulfate (the active ingredients of Primidone and Dexedrine, respectively), and Primidone and Dexedrine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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