Prinivil and Cyanocobalamin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prinivil (lisinopril) and Cyanocobalamin (cyanocobalamin). Common drug interactions include adjustment disorder with depressed mood among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Prinivil and Cyanocobalamin. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Prinivil?

Prinivil has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 20,152 Prinivil users. Check the latest studies of Prinivil.

What is Cyanocobalamin?

Cyanocobalamin has active ingredients of cyanocobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 14,651 Cyanocobalamin users. Check the latest studies of Cyanocobalamin.



On Jul, 27, 2026

36 people who take Prinivil and Cyanocobalamin together, and have interactions are studied.

Prinivil and Cyanocobalamin drug interactions.

What are the common drug interactions of Prinivil and Cyanocobalamin, by gender? *:

female:

  1. Adjustment disorder with depressed mood
  2. Adverse drug reaction
  3. Ageusia (loss of taste functions of the tongue)
  4. Agitation (state of anxiety or nervous excitement)
  5. Alopecia (absence of hair from areas of the body)
  6. Anaemia (lack of blood)
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Anti-cyclic citrullinated peptide antibody positive
  9. Arrhythmia (irregular heartbeat)
  10. Arteriosclerosis (thickening and hardening of arteries)

male:

  1. Abdominal discomfort
  2. Kidney infection
  3. Faeces discoloured
  4. Fatigue (feeling of tiredness)
  5. Haemoglobin decreased
  6. Hepatitis (inflammation of the liver)
  7. Hospitalisation
  8. Malignant neoplasm progression (cancer tumour came back)
  9. Oedema peripheral (superficial swelling)
  10. Pancreatitis acute (sudden inflammation of pancreas)

What are the common drug interactions of Prinivil and Cyanocobalamin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cardiomyopathy (weakening of the heart muscle)
  2. Cataract (clouding of the lens inside the eye)
  3. Cerebral atrophy (decrement in size of brain)
  4. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  5. Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
  6. Confusional state
  7. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  8. Deafness
  9. Decreased activity
  10. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

40-49:

n/a

50-59:

  1. Cystitis (inflammation of the wall of the bladder)
  2. Herpes simplex (herpes simplex is a common viral infection)
  3. Small intestinal obstruction (blockage in small intestine)
  4. Chronic kidney disease
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Memory impairment
  8. Neuralgia (pain in one or more nerves)

60+:

  1. Back pain
  2. Dizziness
  3. Oedema (fluid collection in tissue)
  4. Swelling face
  5. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  6. Appetite disorder (abnormal eating habits)
  7. Ascites (accumulation of fluid in the abdominal cavity)
  8. Blood bilirubin increased
  9. Constipation
  10. Cough

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 9 people, 25.00%
  2. Stress And Anxiety: 7 people, 19.44%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 19.44%
  4. Type 2 Diabetes: 6 people, 16.67%
  5. Pain: 6 people, 16.67%
  6. Nausea And Vomiting: 6 people, 16.67%
  7. Blood Iron Decreased: 5 people, 13.89%
  8. Essential Hypertension (primary hypertension): 5 people, 13.89%
  9. Fever: 5 people, 13.89%
  10. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 5 people, 13.89%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prinivil and Cyanocobalamin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prinivil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cyanocobalamin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prinivil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cyanocobalamin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lisinopril and cyanocobalamin (the active ingredients of Prinivil and Cyanocobalamin, respectively), and Prinivil and Cyanocobalamin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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