Prinivil and Opana drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prinivil (lisinopril) and Opana (oxymorphone hydrochloride). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Prinivil and Opana. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Prinivil?

Prinivil has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 20,152 Prinivil users. Check the latest studies of Prinivil.

What is Opana?

Opana has active ingredients of oxymorphone hydrochloride. It is often used in pain. eHealthMe is studying from 40,340 Opana users. Check the latest studies of Opana.

On Jul, 29, 2026

12 people who take Prinivil and Opana together, and have interactions are studied.

What are the common drug interactions of Prinivil and Opana, by gender? *:

female:

Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Acute stress disorder
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Atrophic vulvovaginitis (inflammation of the vulva)
Brain injury
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cardiac disorder
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))

male:

Chronic kidney disease
Osteonecrosis (death of bone)
Tooth loss
Wrist fracture
Emotional distress
Gait disturbance
Infection
Mobility decreased (ability to move is reduced)
Osteoporotic fracture (fracture due to weak bone)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the common drug interactions of Prinivil and Opana, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Osteonecrosis (death of bone)
Hip arthroplasty
Bone density decreased
Bone loss
Chronic kidney disease
Knee arthroplasty
Multiple fractures
Osteopenia (a condition where bone mineral density is lower than normal)
Renal failure (kidney dysfunction)
Rib fracture

40-49:

Chronic kidney disease

50-59:

n/a

60+:

Chronic kidney disease
Dizziness postural
Loss of consciousness
Renal failure (kidney dysfunction)
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Fall
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haemorrhage (bleeding)
Head injury

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 58.33%
Wound: 5 people, 41.67%
Infection: 5 people, 41.67%
Back Pain: 5 people, 41.67%
Depression: 5 people, 41.67%
High Blood Cholesterol: 5 people, 41.67%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 41.67%
Oedema (fluid collection in tissue): 5 people, 41.67%
Heart Attack: 4 people, 33.33%
Stress And Anxiety: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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