Ultram er and Seroquel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ultram er (tramadol hydrochloride) and Seroquel (quetiapine fumarate). Common drug interactions include agitation among females and diabetic neuropathy among males.

The phase IV clinical study analyzes what interactions people have when they take Ultram er and Seroquel. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Ultram er?

Ultram er has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 1,387 Ultram er users. Check the latest studies of Ultram er.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.

On Jul, 29, 2026

19 people who take Ultram er and Seroquel together, and have interactions are studied.

Ultram er and Seroquel drug interactions.

What are the common drug interactions of Ultram Er and Seroquel, by gender? *:

female:

Agitation (state of anxiety or nervous excitement)
Drooling (drop saliva uncontrollably from the mouth)
Drug hypersensitivity
Glossitis (infection of tongue with soreness)
Hypoacusis (loss of hearing)
Lethargy (tiredness)
Mania (a state of abnormally elevated or irritable mood)
Oral pain
Swelling
Aphonia (inability to produce voice)

male:

Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Type 2 diabetes mellitus
Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
Hypotension (abnormally low blood pressure)
Ingrowing nail
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Obesity (having too much body fat)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Paronychia (infection in the tissues adjacent to a nail on a finger or toe)

What are the common drug interactions of Ultram Er and Seroquel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Hyperthyroidism (over activity of the thyroid gland)
Neutropenia (an abnormally low number of neutrophils)
Anaemia (lack of blood)
Arthralgia (joint pain)
Burning feet syndrome (burning sensation in the sole of the foot)
Carbuncle (a carbuncle is an abscess larger than a boil)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Furuncle (infection of the hair follicle)
Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)

40-49:

Blood cholesterol increased
Diabetes mellitus inadequate control
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Hyperlipidaemia (presence of excess lipids in the blood)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Type 2 diabetes mellitus
Weight increased
Menstrual disorder (disease of menstrual cycle)

50-59:

Drooling (drop saliva uncontrollably from the mouth)
Drug hypersensitivity
Fatigue (feeling of tiredness)
Gait disturbance
Glossitis (infection of tongue with soreness)
Hepatitis (inflammation of the liver)
Hypoacusis (loss of hearing)
Hypoaesthesia (reduced sense of touch or sensation)
Lethargy (tiredness)
Mania (a state of abnormally elevated or irritable mood)

60+:

Dehydration (dryness resulting from the removal of water)
Diarrhoea
Dysgeusia (disorder of the sense of taste)
Malaise (a feeling of general discomfort or uneasiness)
Viral infection

What are the existing conditions these people have? *

Chronic Fatigue Syndrome (disorder that causes extreme fatigue): 5 people, 26.32%
High Blood Pressure: 3 people, 15.79%
Indigestion: 3 people, 15.79%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 3 people, 15.79%
Diabetes: 3 people, 15.79%
Hypersensitivity: 3 people, 15.79%
Asthma: 2 people, 10.53%
Blood Pressure Abnormal: 2 people, 10.53%
Cardiac Disorder: 2 people, 10.53%
Chest Pain: 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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