Pristiq and Meloxicam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pristiq (desvenlafaxine succinate) and Meloxicam (meloxicam). Common drug interactions include influenza like illness among females and euphoric mood among males.

The phase IV clinical study analyzes what interactions people have when they take Pristiq and Meloxicam. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.

What is Pristiq?

Pristiq has active ingredients of desvenlafaxine succinate. It is often used in depression. eHealthMe is studying from 19,555 Pristiq users. Check the latest studies of Pristiq.

What is Meloxicam?

Meloxicam has active ingredients of meloxicam. It is often used in arthritis. eHealthMe is studying from 68,017 Meloxicam users. Check the latest studies of Meloxicam.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

72 people who take Pristiq and Meloxicam together, and have interactions are studied.

Pristiq and Meloxicam drug interactions.

What are the common drug interactions of Pristiq and Meloxicam, by gender? *:

female:

Influenza like illness
Neuropathy peripheral (surface nerve damage)
Pain in extremity
Renal neoplasm (kidney tumour)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Suicide attempt
Abdominal discomfort
Alopecia (absence of hair from areas of the body)
Asthenia (weakness)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

male:

Euphoric mood (excessively happy but may become angry or irritable)
Hearing impaired
Irritability
Lethargy (tiredness)
Nausea (feeling of having an urge to vomit)
Rectal haemorrhage (bleeding from anus)
Somnolence (a state of near-sleep, a strong desire for sleep)
Abdominal pain
Abscess (pus)
Activities of daily living impaired

What are the common drug interactions of Pristiq and Meloxicam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Intracranial venous sinus thrombosis (presence of thrombosis (a blood clot) in the dural venous sinuses, which drain blood from the brain)

30-39:

Dizziness
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dysarthria (speech disorder)
Nausea (feeling of having an urge to vomit)
Rib fracture
Alopecia (absence of hair from areas of the body)
Breast cancer female
Diarrhoea
Eye swelling
Injection site pain

40-49:

Fatigue (feeling of tiredness)
Aerophagia (excessive air swallowing)
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Bilirubinuria (presence of bilirubin in urine)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Decreased appetite
Dysphagia (a condition in which swallowing is difficult or painful)
Eructation (release of gas from the digestive tract)
Hepatic enzyme increased
Hyperhidrosis (abnormally increased sweating)

50-59:

Lumbar radiculopathy (radicular pain in the low back and legs)
Memory impairment
Multiple fractures
Muscle atrophy (a decrease in the mass of the muscle)
Muscle fatigue (a condition in which muscles cannot exert their normal force)
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Myalgia (muscle pain)

60+:

Breast mass
Crying
Panic attack
Rectal haemorrhage (bleeding from anus)
Acute respiratory distress syndrome
Alopecia (absence of hair from areas of the body)
Anorgasmia (type of sexual dysfunction in which a person cannot achieve orgasm, even with adequate stimulation)
Blood disorder
Bone density decreased
Bone loss

What are the existing conditions these people have? *

Pain: 11 people, 15.28%
Bipolar Disorder (mood disorder): 9 people, 12.50%
Stress And Anxiety: 8 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 9.72%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 8.33%
Indigestion: 5 people, 6.94%
High Blood Pressure: 5 people, 6.94%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 6.94%
Multiple Myeloma (cancer of the plasma cells): 4 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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