Proamatine and Cordarone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Proamatine (midodrine hydrochloride) and Cordarone (amiodarone hydrochloride). Common drug interactions include death among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Proamatine and Cordarone. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Proamatine?

Proamatine has active ingredients of midodrine hydrochloride. It is often used in hypotension. eHealthMe is studying from 968 Proamatine users. Check the latest studies of Proamatine.

What is Cordarone?

Cordarone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 22,776 Cordarone users. Check the latest studies of Cordarone.

On Jul, 12, 2026

16 people who take Proamatine and Cordarone together, and have interactions are studied.

Proamatine and Cordarone drug interactions.

What are the common drug interactions of Proamatine and Cordarone, by gender? *:

female:

Death
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

male:

Dizziness
Fall
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Coagulopathy (blood's ability to clot is impaired)
Confusional state
Decreased appetite
Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Rash
Type 2 diabetes mellitus

What are the common drug interactions of Proamatine and Cordarone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Coagulopathy (blood's ability to clot is impaired)
Confusional state
Decreased appetite
Dizziness
Dyspnoea (difficult or laboured respiration)
Lethargy (tiredness)
Nausea (feeling of having an urge to vomit)
Rash
Type 2 diabetes mellitus

50-59:

n/a

60+:

Fall
Anaemia (lack of blood)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arteriovenous fistula thrombosis (formation of a blood clot inside a blood vessel-av fistula)
Coagulopathy (blood's ability to clot is impaired)
Confusional state
Decreased appetite
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Dyspnoea (difficult or laboured respiration)
Fluid overload (too much fluid in the blood)

What are the existing conditions these people have? *

Stable Angina (a constant chest pain): 3 people, 18.75%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 3 people, 18.75%
Gout (uric acid crystals building up in the body): 3 people, 18.75%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 3 people, 18.75%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 12.50%
Urinary Tract Infection: 1 person, 6.25%
Urinary Retention (the inability to completely or partially empty the bladder): 1 person, 6.25%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 6.25%
Sleep Disorder: 1 person, 6.25%
Skin Irritation: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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