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Probenecid and Prednisolone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Probenecid (probenecid) and Prednisolone (prednisolone). Common drug interactions include balance disorder among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Probenecid and Prednisolone. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Probenecid?

Probenecid has active ingredients of probenecid. It is often used in gout. eHealthMe is studying from 560 Probenecid users. Check the latest studies of Probenecid.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.



On Jul, 24, 2026

42 people who take Probenecid and Prednisolone together, and have interactions are studied.

Probenecid and Prednisolone drug interactions.

What are the common drug interactions of Probenecid and Prednisolone, by gender? *:

female:

  1. Balance disorder
  2. Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
  3. Dysarthria (speech disorder)
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Jc virus infection
  6. Nystagmus (a condition of involuntary eye movement)
  7. Past-pointing
  8. Pneumonia
  9. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  10. Respiratory failure (inadequate gas exchange by the respiratory system)

male:

  1. Anxiety
  2. Bone pain
  3. Swelling
  4. Arteriosclerosis (thickening and hardening of arteries)
  5. Arteriovenous fistula
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Cardiac failure congestive
  8. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  9. Device related infection
  10. Gastritis (inflammation of stomach)

What are the common drug interactions of Probenecid and Prednisolone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Adenovirus infection
  2. Lymphopenia (an abnormally low level of lymphocytes in the blood)
  3. Abdominal pain
  4. Bacterial infection
  5. Diarrhoea
  6. Infection
  7. Pancreatitis acute (sudden inflammation of pancreas)
  8. Vomiting
  9. Encephalitis (inflammation of the brain)
  10. Neurological symptom (symptoms of nervous system disease)

10-19:

  1. Abdominal pain
  2. Adenovirus infection
  3. Bacterial infection
  4. Diarrhoea
  5. Pancreatitis acute (sudden inflammation of pancreas)
  6. Pyrexia (fever)
  7. Vomiting

20-29:

n/a

30-39:

n/a

40-49:

  1. Alanine aminotransferase increased
  2. Aspartate aminotransferase increased
  3. Gamma-glutamyltransferase increased
  4. Liver disorder (liver diseases)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)

50-59:

  1. Respiratory failure (inadequate gas exchange by the respiratory system)
  2. Acute hepatic failure
  3. Hepatitis (inflammation of the liver)
  4. Pneumonia adenoviral (viral pneumonia caused by an adenovirus)
  5. Renal failure (kidney dysfunction)
  6. Drug ineffective
  7. Adenovirus infection
  8. Anaemia (lack of blood)
  9. Angioimmunoblastic t-cell lymphoma (mature t-cell cancer of the blood or lymph vessel)
  10. Atypical pneumonia (acute respiratory disease marked by high fever and coughing)

60+:

  1. Anxiety
  2. Bone pain
  3. Arteriosclerosis (thickening and hardening of arteries)
  4. Arteriovenous fistula
  5. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  6. Cardiac failure congestive
  7. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  8. Device related infection
  9. Disability
  10. Dysphagia (a condition in which swallowing is difficult or painful)

What are the existing conditions these people have? *

  1. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 9.52%
  2. Premature Menopause: 4 people, 9.52%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 9.52%
  4. Hypersensitivity: 4 people, 9.52%
  5. Pain: 3 people, 7.14%
  6. Osteoporosis (bones weak and more likely to break): 3 people, 7.14%
  7. Atypical Mycobacterial Infection (infections caused by several types of mycobacterium similar to the germ that causes tuberculosis): 3 people, 7.14%
  8. Angioimmunoblastic T-Cell Lymphoma (mature t-cell cancer of the blood or lymph vessel): 3 people, 7.14%
  9. Adenovirus Infection: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Probenecid and Prednisolone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Probenecid and Prednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Probenecid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Probenecid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prednisolone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on probenecid and prednisolone (the active ingredients of Probenecid and Prednisolone, respectively), and Probenecid and Prednisolone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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