Probenecid and Ursodiol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Probenecid (probenecid) and Ursodiol (ursodiol). Common drug interactions include aplastic anaemia among females and acute graft versus host disease among males.

The phase IV clinical study analyzes what interactions people have when they take Probenecid and Ursodiol. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Probenecid?

Probenecid has active ingredients of probenecid. It is often used in gout. eHealthMe is studying from 560 Probenecid users. Check the latest studies of Probenecid.

What is Ursodiol?

Ursodiol has active ingredients of ursodiol. It is often used in primary biliary cirrhosis. eHealthMe is studying from 19,061 Ursodiol users. Check the latest studies of Ursodiol.

On Jul, 05, 2026

18 people who take Probenecid and Ursodiol together, and have interactions are studied.

Probenecid and Ursodiol drug interactions.

What are the common drug interactions of Probenecid and Ursodiol, by gender? *:

female:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Febrile neutropenia (fever with reduced white blood cells)
Mucosal inflammation (infection of mucous membrane)
Renal failure (kidney dysfunction)
Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
Pneumonia

male:

Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Renal failure acute (rapid kidney dysfunction)
Pulmonary haemorrhage (acute bleeding from the lung)
Pulmonary oedema (fluid accumulation in the lungs)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Respiratory failure (inadequate gas exchange by the respiratory system)
Unresponsive to stimuli
Acute graft versus host disease in intestine (acute complication in intestine following an allogeneic tissue/blood transplant)
Acute graft versus host disease in liver (acute complication in liver following an allogeneic tissue/blood transplant)
Lung infection

What are the common drug interactions of Probenecid and Ursodiol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Depressed level of consciousness
Febrile neutropenia (fever with reduced white blood cells)
Mucosal inflammation (infection of mucous membrane)

10-19:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)

20-29:

Respiratory distress (difficulty in breathing)
Acute respiratory failure
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Herpes simplex ophthalmic (eye infection is caused by a type of herpes simplex virus)
Pneumonia
Pneumonia fungal
Pneumonia viral
Pulmonary haemorrhage (acute bleeding from the lung)
Pulmonary oedema (fluid accumulation in the lungs)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)

30-39:

n/a

40-49:

n/a

50-59:

Acute graft versus host disease in intestine (acute complication in intestine following an allogeneic tissue/blood transplant)
Acute graft versus host disease in liver (acute complication in liver following an allogeneic tissue/blood transplant)
Lung infection
Sepsis (a severe blood infection that can lead to organ failure and death)

60+:

Renal failure (kidney dysfunction)
Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
Pneumonia

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 27.78%
High Blood Pressure: 4 people, 22.22%
Thrombocytopenia (decrease of platelets in blood): 3 people, 16.67%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 3 people, 16.67%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 16.67%
Adenovirus Infection: 3 people, 16.67%
Anaemia (lack of blood): 3 people, 16.67%
Candidiasis (candidiasis or thrush is a fungal infection): 3 people, 16.67%
Electrocardiogram Qt Prolonged: 3 people, 16.67%
Rectal Fissure (painful condition in which a cut or tear occurs in the anus): 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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