Probiotics and Opdivo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Probiotics (yogurt) and Opdivo (nivolumab). Common drug interactions include anaemia among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Probiotics and Opdivo. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Probiotics?

Probiotics has active ingredients of yogurt. It is often used in irritable bowel syndrome. eHealthMe is studying from 9,541 Probiotics users. Check the latest studies of Probiotics.

What is Opdivo?

Opdivo has active ingredients of nivolumab. eHealthMe is studying from 56,331 Opdivo users. Check the latest studies of Opdivo.



On Jul, 19, 2026

66 people who take Probiotics and Opdivo together, and have interactions are studied.

Probiotics and Opdivo drug interactions.

What are the common drug interactions of Probiotics and Opdivo, by gender? *:

female:

  1. Anaemia (lack of blood)
  2. Autoimmune myocarditis (inflammation of the heart muscle by immune system disorder)
  3. Blood cholesterol increased
  4. Blood thyroid stimulating hormone increased
  5. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  6. Cystitis (inflammation of the wall of the bladder)
  7. Dysgeusia (disorder of the sense of taste)
  8. Dysphonia (speech disorder attributable to a disorder of phonation)
  9. Dyspnoea exertional (breathlessness or shortness of breath)
  10. Escherichia urinary tract infection (urinary tract infection by escherichia coli)

male:

  1. Diarrhoea
  2. Fatigue (feeling of tiredness)
  3. Colitis (inflammation of colon)
  4. Osteonecrosis (death of bone)
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Dry skin
  7. Skin exfoliation (removal of the oldest dead skin cells)
  8. Cough
  9. Dry mouth
  10. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)

What are the common drug interactions of Probiotics and Opdivo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Dysphonia (speech disorder attributable to a disorder of phonation)
  2. Nail pigmentation (nail colour)
  3. Onychalgia (nail biting)
  4. Cough
  5. Diarrhoea
  6. Dry mouth
  7. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
  8. Malignant neoplasm progression (cancer tumour came back)

50-59:

  1. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  2. Hepatic pain (pain in liver)
  3. Fatigue (feeling of tiredness)
  4. Diarrhoea
  5. Dry skin
  6. Skin exfoliation (removal of the oldest dead skin cells)
  7. Abdominal discomfort
  8. Abdominal pain upper
  9. Alanine aminotransferase increased
  10. Aspartate aminotransferase increased

60+:

  1. Fatigue (feeling of tiredness)
  2. Decreased appetite
  3. Rash
  4. Back pain
  5. Blood creatinine increased
  6. Blood glucose increased
  7. Chest pain
  8. Dyspnoea (difficult or laboured respiration)
  9. Foot deformity (functional disability of foot)
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 33 people, 50.00%
  2. Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 8 people, 12.12%
  3. Metastases To Lung (cancer spreads to lung): 5 people, 7.58%
  4. Pain: 4 people, 6.06%
  5. Oral Cancer (mouth cancer): 4 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Probiotics and Opdivo?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Probiotics and Opdivo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Probiotics:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Opdivo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Probiotics and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Opdivo and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on yogurt and nivolumab (the active ingredients of Probiotics and Opdivo, respectively), and Probiotics and Opdivo (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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