Procardia and Codeine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Procardia (nifedipine) and Codeine (codeine sulfate). Common drug interactions include diarrhoea among females and anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Procardia and Codeine. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.
What is Procardia?
Procardia has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 15,151 Procardia users. Check the latest studies of Procardia.
What is Codeine?
Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.
55 people who take Procardia and Codeine together, and have interactions are studied.

What are the common drug interactions of Procardia and Codeine, by gender? *:
female:
- Diarrhoea
- Hypotension (abnormally low blood pressure)
- Osteoporosis (bones weak and more likely to break)
- Pruritus (severe itching of the skin)
- Restlessness (not able to rest)
- Arteriovenous fistula thrombosis (formation of a blood clot inside a blood vessel-av fistula)
- Arthralgia (joint pain)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cellulitis (infection under the skin)
male:
- Anxiety
- Abdominal pain upper
- Aspartate aminotransferase increased
- Asthenia (weakness)
- Back disorder
- Bile duct stone
- Blood alkaline phosphatase increased
- Blood bilirubin increased
- Blood calcium decreased
- Blood creatinine decreased
What are the common drug interactions of Procardia and Codeine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Headache (pain in head)
- Agitation (state of anxiety or nervous excitement)
- Aphasia (damage to the parts of the brain that control language)
- Arthralgia (joint pain)
- Balance disorder
- Cogwheel rigidity (tension in a muscle which gives way in little jerks when the muscle is stretched)
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Diarrhoea
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Dizziness
30-39:
- Anal abscess
- Cellulitis (infection under the skin)
- Drug hypersensitivity
- Genital abscess (build up of pus in genital)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Scrotal abscess (pus in scrotum)
- Scrotal oedema (swelling of scrotum)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Testicular necrosis (damaged testes)
- Urinary tract infection
40-49:
- Anxiety
- Arthralgia (joint pain)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Chest pain
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Epicondylitis (tennis elbow)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Hallucination, auditory (perceiving sounds without auditory stimulus)
- Headache (pain in head)
50-59:
- Dyskinesia (abnormality or impairment of voluntary movement)
- Dysuria (painful or difficult urination)
- Herpes zoster
- Hot flush (sudden feelings of heat)
- Hyperhidrosis (abnormally increased sweating)
- Impaired driving ability
- Insomnia (sleeplessness)
- Panic attack
- Tinnitus (a ringing in the ears)
- Uterine leiomyoma (uterine benign tumour derived from smooth muscle)
60+:
- Drug hypersensitivity
- Cardiac failure congestive
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Anxiety
- Aortic valve stenosis (narrowing of the aortic valve)
- Arrhythmia (irregular heartbeat)
- Asbestosis (chronic lung disease caused by scarring of lung tissue, which stems from prolonged exposure to asbestos)
- Aspartate aminotransferase increased
- Asthenia (weakness)
- Back disorder
What are the existing conditions these people have? *
- High Blood Cholesterol: 4 people, 7.27%
- Haemorrhage (bleeding): 4 people, 7.27%
- Breast Cancer Metastatic: 4 people, 7.27%
- Aortic Valve Incompetence: 4 people, 7.27%
* Approximation only. Some reports may have incomplete information.
Do you take Procardia and Codeine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Procardia and Codeine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Procardia:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Codeine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Procardia and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Codeine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nifedipine and codeine sulfate (the active ingredients of Procardia and Codeine, respectively), and Procardia and Codeine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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