Procardia and Jakafi drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Procardia (nifedipine) and Jakafi (ruxolitinib phosphate). Common drug interactions include dizziness among females and acute myeloid leukaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Procardia and Jakafi. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.
What is Procardia?
Procardia has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 15,151 Procardia users. Check the latest studies of Procardia.
What is Jakafi?
Jakafi has active ingredients of ruxolitinib phosphate. It is often used in primary myelofibrosis. eHealthMe is studying from 56,530 Jakafi users. Check the latest studies of Jakafi.
40 people who take Procardia and Jakafi together, and have interactions are studied.

What are the common drug interactions of Procardia and Jakafi, by gender? *:
female:
- Dizziness
- Haemoglobin decreased
- Inner ear disorder
- Mouth haemorrhage (bleeding from mouth)
- Death
- Epistaxis (bleed from the nose)
- Eye haemorrhage (bleeding in the eye)
- Fall
- Rash
- Syncope (loss of consciousness with an inability to maintain postural tone)
male:
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
- Fatigue (feeling of tiredness)
- Pneumonia
- Vision blurred
- Aspartate aminotransferase increased
- Blood urea increased
- Blood urea nitrogen/creatinine ratio increased
- Bone pain
- Death
- Dizziness
What are the common drug interactions of Procardia and Jakafi, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
- Aspartate aminotransferase increased
- Blood urea increased
- Blood urea nitrogen/creatinine ratio increased
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
- Hospitalisation
- Viraemia (presence of a virus in the blood stream)
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Epistaxis (bleed from the nose)
60+:
- Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Headache (pain in head)
- Pneumonia
- Vision blurred
- Bone pain
- Pain in extremity
- Platelet count decreased
- Rash
- White blood cell count decreased
What are the existing conditions these people have? *
- Essential Thrombocythaemia (chronic blood cancer): 4 people, 10.00%
- Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 3 people, 7.50%
* Approximation only. Some reports may have incomplete information.
Do you take Procardia and Jakafi?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Procardia and Jakafi:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Procardia:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Jakafi:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Procardia and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Jakafi and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nifedipine and ruxolitinib phosphate (the active ingredients of Procardia and Jakafi, respectively), and Procardia and Jakafi (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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