Profen and Caverject drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Caverject (alprostadil). Common drug interactions include drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Profen and Caverject. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Caverject?

Caverject has active ingredients of alprostadil. It is often used in erection problems. eHealthMe is studying from 2,144 Caverject users. Check the latest studies of Caverject.



On Jul, 15, 2026

22 people who take Profen and Caverject together, and have interactions are studied.

Profen and Caverject drug interactions.

What are the common drug interactions of Profen and Caverject, by gender? *:

female:

n/a

male:

  1. Drug ineffective
  2. Anxiety
  3. Fall
  4. Grip strength decreased
  5. Joint range of motion decreased (disease of joint movement)
  6. Mass
  7. Osteopenia (a condition where bone mineral density is lower than normal)
  8. Radius fracture
  9. Road traffic accident
  10. Abdominal hernia

What are the common drug interactions of Profen and Caverject, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Blood creatine phosphokinase increased
  2. Crystal nephropathy (crystal induced injury to kidney)
  3. Liver disorder (liver diseases)
  4. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Bone density decreased
  4. Emotional distress
  5. Fall
  6. Grip strength decreased
  7. Joint range of motion decreased (disease of joint movement)
  8. Mass
  9. Osteopenia (a condition where bone mineral density is lower than normal)
  10. Radius fracture

50-59:

  1. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  2. Erection increased
  3. Testicular disorder (disease of testes)

60+:

  1. Drug ineffective
  2. Chronic kidney disease
  3. Arthralgia (joint pain)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Atrioventricular block first degree (heart block first degree)
  6. Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
  7. Benign prostatic hyperplasia (benign enlargement of the prostate)
  8. Blood glucose decreased
  9. Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
  10. Cardiac failure congestive

What are the existing conditions these people have? *

  1. Depression: 6 people, 27.27%
  2. High Blood Cholesterol: 4 people, 18.18%
  3. Heart Rate Irregular: 4 people, 18.18%
  4. High Blood Pressure: 4 people, 18.18%
  5. Chest Pain: 3 people, 13.64%
  6. Gastric Ulcer (stomach ulcer): 3 people, 13.64%
  7. Blood Uric Acid Increased: 3 people, 13.64%
  8. Headache (pain in head): 3 people, 13.64%
  9. Gout (uric acid crystals building up in the body): 3 people, 13.64%
  10. Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and Caverject?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Profen and Caverject:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Caverject:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Profen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Caverject and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen and alprostadil (the active ingredients of Profen and Caverject, respectively), and Profen and Caverject (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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