Profen and Eldepryl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Eldepryl (selegiline hydrochloride). Common drug interactions include cerebrovascular accident among females and pathological gambling among males.

The phase IV clinical study analyzes what interactions people have when they take Profen and Eldepryl. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Eldepryl?

Eldepryl has active ingredients of selegiline hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 752 Eldepryl users. Check the latest studies of Eldepryl.

On Jul, 31, 2026

15 people who take Profen and Eldepryl together, and have interactions are studied.

What are the common drug interactions of Profen and Eldepryl, by gender? *:

female:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Haemorrhage (bleeding)
Paralysis
Purpura (purplish discoloration of the skin)

male:

Pathological gambling
Emotional distress
Psychotic disorder
Weight increased
Asthenia (weakness)
Depression
Insomnia (sleeplessness)
Suicidal ideation
Abdominal distension
Abdominal pain

What are the common drug interactions of Profen and Eldepryl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Asthenia (weakness)
Abdominal distension
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Arthropathy
Ataxia (loss of full control of bodily movements)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)

What are the existing conditions these people have? *

Depression: 7 people, 46.67%
Insomnia (sleeplessness): 5 people, 33.33%
Genital Herpes (herpes infection of genital): 5 people, 33.33%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 5 people, 33.33%
Curvature Of The Penis: 5 people, 33.33%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 33.33%
Nasal Discharge (discharge from nose): 5 people, 33.33%
Agitation (state of anxiety or nervous excitement): 4 people, 26.67%
Muscle Rigidity (muscle stiffness): 2 people, 13.33%
Erection Problems: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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