Profen and Elestat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Elestat (epinastine hydrochloride). Common drug interactions include unresponsive to stimuli among females and abscess limb among males.

The phase IV clinical study analyzes what interactions people have when they take Profen and Elestat. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Elestat?

Elestat has active ingredients of epinastine hydrochloride. eHealthMe is studying from 213 Elestat users. Check the latest studies of Elestat.

On Jul, 28, 2026

13 people who take Profen and Elestat together, and have interactions are studied.

What are the common drug interactions of Profen and Elestat, by gender? *:

female:

Unresponsive to stimuli
Ventricular extrasystoles (premature cardiac contraction)
Viith nerve paralysis
Chronic kidney disease
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Fall
Nausea (feeling of having an urge to vomit)
Vomiting
Abdominal pain upper
Abdominal tenderness

male:

Abscess limb (limb infection)
Cellulitis (infection under the skin)
Anal abscess
Emotional distress
Genital abscess (build up of pus in genital)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Sepsis (a severe blood infection that can lead to organ failure and death)
Cellulitis of male external genital organ (infection of male genitals soft tissue)
Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
Gangrene (body tissue dies)

What are the common drug interactions of Profen and Elestat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Pulmonary embolism (blockage of the main artery of the lung)
Abdominal pain upper
Abdominal tenderness
Cholecystitis (infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dyspepsia (indigestion)
Vomiting

30-39:

n/a

40-49:

Abscess limb (limb infection)
Cellulitis (infection under the skin)
Cellulitis of male external genital organ (infection of male genitals soft tissue)
Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
Gangrene (body tissue dies)
Groin abscess (pus in groin)
Leukocytosis (increased white blood cells)
Scrotal abscess (pus in scrotum)
Testicular abscess (pus in testes)
Tooth abscess (pus formation in tooth)

50-59:

n/a

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Chronic kidney disease
Renal tubular necrosis (death of kidney tubules)
Acquired macroglossia (large tongue)
Acute respiratory failure
Anticonvulsant drug level above therapeutic
Anxiety
Aortic valve sclerosis (narrowing of the aortic valve)
Arrhythmia (irregular heartbeat)
Atrial hypertrophy (a condition where the left atrium or right atrium of the heart is larger than would be expected)

What are the existing conditions these people have? *

Infection: 5 people, 38.46%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 38.46%
Asthma: 4 people, 30.77%
Constipation: 4 people, 30.77%
Hypersensitivity: 3 people, 23.08%
Back Pain: 2 people, 15.38%
Cough: 2 people, 15.38%
Dry Eyes (lack of adequate tears): 2 people, 15.38%
Eye Infection: 2 people, 15.38%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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