Profen and Fml drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Fml (fluorometholone). Common drug interactions include white blood cell count decreased among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Profen and Fml. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Fml?

Fml has active ingredients of fluorometholone. eHealthMe is studying from 673 Fml users. Check the latest studies of Fml.

On Jul, 26, 2026

22 people who take Profen and Fml together, and have interactions are studied.

What are the common drug interactions of Profen and Fml, by gender? *:

female:

White blood cell count decreased
Bone loss
Breast cancer metastatic
Cardiomegaly (increased size of heart than normal)
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Dizziness
Emotional distress
Fatigue (feeling of tiredness)
Gingival bleeding (bleeding gums)
Gingival erosion (gum ulcer)

male:

Abdominal pain
Blood corticotrophin increased
Pyrexia (fever)
Quality of life decreased
Sepsis (a severe blood infection that can lead to organ failure and death)
Stomatitis (inflammation of mucous membrane of mouth)
Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
Decreased appetite
Diarrhoea
Dysphonia (speech disorder attributable to a disorder of phonation)

What are the common drug interactions of Profen and Fml, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Impaired work ability

50-59:

Breast cancer metastatic
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Eye pruritus (eye itching)
Eye swelling
Glomerular filtration rate decreased
Post procedural infection
Staphylococcal infection (an infection with staphylococcus bacteria)
Dizziness
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Poor venous access

60+:

Quality of life decreased
Bone loss
Loose tooth
Nausea (feeling of having an urge to vomit)
Nephrolithiasis (calculi in the kidneys)
Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
Osteonecrosis of jaw (death of bone of jaw)
Ovarian cyst (fluid filled sac of the ovary)
Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery)
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 4 people, 18.18%
Insulin Resistance: 3 people, 13.64%
Immunodeficiency Common Variable: 3 people, 13.64%
Neuralgia (pain in one or more nerves): 2 people, 9.09%
Muscle Spasms (muscle contraction): 2 people, 9.09%
Multiple Myeloma (cancer of the plasma cells): 2 people, 9.09%
Mouth Ulcers: 2 people, 9.09%
High Blood Pressure: 2 people, 9.09%
High Blood Cholesterol: 2 people, 9.09%
Headache (pain in head): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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