Profen and Folvite drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Folvite (folic acid). Common drug interactions include nausea among females and pruritus among males.

The phase IV clinical study analyzes what interactions people have when they take Profen and Folvite. It is created by eHealthMe based on reports of 98 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Folvite?

Folvite has active ingredients of folic acid. eHealthMe is studying from 2,529 Folvite users. Check the latest studies of Folvite.

On Jul, 09, 2026

98 people who take Profen and Folvite together, and have interactions are studied.

What are the common drug interactions of Profen and Folvite, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Pain in extremity
Chest pain
Headache (pain in head)
Influenza
Oedema peripheral (superficial swelling)
Respiratory failure (inadequate gas exchange by the respiratory system)
Urinary tract infection

male:

Pruritus (severe itching of the skin)
Dyspnoea (difficult or laboured respiration)
Small intestinal obstruction (blockage in small intestine)
Vomiting
Abdominal pain
Anaemia of malignant disease
Anaemia vitamin b12 deficiency
Anxiety
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)

What are the common drug interactions of Profen and Folvite, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Abdominal pain
Cholangitis (infection of the bile duct)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Diarrhoea
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Fungaemia (fungi circulate in the blood)
Gallbladder disorder
Groin pain
Kidney enlargement
Liver disorder (liver diseases)

10-19:

Colitis ulcerative (inflammation of colon with ulcer)
Abdominal abscess (collection of pus in abdomen)
Ileal stenosis (obstruction in the ileal)
Tooth impacted (a tooth that fails to fully pass through the gums)
Anastomotic complication (complication of surgical connection between two structures)
Anastomotic leak
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bacteraemia (presence of bacteria in the blood)
Blood pressure systolic increased

20-29:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Maternal exposure during pregnancy (use of substance during pregnancy)
Overdose
Staring (a prolonged gaze or fixed look)
Tremor (trembling or shaking movements in one or more parts of your body)
Live birth
Acute chest syndrome (acute chest pain, fever and difficulty breathing)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

30-39:

Premature labour
Abdominal discomfort
Anaphylactic reaction (serious allergic reaction)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Constipation
Cough
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug abuse

40-49:

Dyspnoea (difficult or laboured respiration)
Chest pain
Haemoglobin decreased
Headache (pain in head)
Hospitalisation
Influenza
Nausea (feeling of having an urge to vomit)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Platelet count decreased

50-59:

Adrenal disorder
Agitation (state of anxiety or nervous excitement)
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood creatinine increased
Calcinosis (calcium deposits in any soft tissue)
Cancer pain
Chronic kidney disease

60+:

Abdominal pain
Arthralgia (joint pain)
Headache (pain in head)
Hypertension (high blood pressure)
Dizziness
Leukopenia (less number of white blood cells in blood)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces)
Small intestinal obstruction (blockage in small intestine)
Hypokalaemia (low potassium)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 14 people, 14.29%
Stress And Anxiety: 13 people, 13.27%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 12.24%
Sleep Disorder: 10 people, 10.20%
Muscle Spasms (muscle contraction): 9 people, 9.18%
Itching: 8 people, 8.16%
Constipation: 7 people, 7.14%
Wheezing (a high-pitched whistling sound made while you breath): 6 people, 6.12%
High Blood Pressure: 6 people, 6.12%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 5 people, 5.10%

* Approximation only. Some reports may have incomplete information.

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