Profen and Fortaz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Fortaz (ceftazidime). Common drug interactions include depression among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Profen and Fortaz. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Fortaz?

Fortaz has active ingredients of ceftazidime. eHealthMe is studying from 980 Fortaz users. Check the latest studies of Fortaz.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 23, 2026

18 people who take Profen and Fortaz together, and have interactions are studied.

Profen and Fortaz drug interactions.

What are the common drug interactions of Profen and Fortaz, by gender? *:

female:

  1. Depression
  2. Streptococcal sepsis (whole body inflammation by streptococcal)
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Vascular insufficiency
  5. General physical health deterioration (weak health status)
  6. Pleural effusion (water on the lungs)
  7. Abdominal pain
  8. Anastomotic leak
  9. Arthralgia (joint pain)
  10. Benign neoplasm of thyroid gland (benign (non-cancerous) tumours of the thyroid gland)

male:

  1. Abdominal distension
  2. Abdominal pain
  3. Abdominal pain lower
  4. Constipation
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Faeces hard
  7. Haematochezia (passage of stools containing blood)
  8. Neutropenia (an abnormally low number of neutrophils)
  9. Pyrexia (fever)
  10. Rectal haemorrhage (bleeding from anus)

What are the common drug interactions of Profen and Fortaz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Alanine aminotransferase increased
  2. Aspartate aminotransferase increased
  3. Gamma-glutamyltransferase increased
  4. Hepatic enzyme increased

10-19:

  1. Abdominal abscess (collection of pus in abdomen)
  2. Anastomotic leak
  3. Ileal stenosis (obstruction in the ileal)

20-29:

n/a

30-39:

  1. Abdominal distension
  2. Abdominal pain
  3. Abdominal pain lower
  4. Constipation
  5. Faeces hard
  6. Haematochezia (passage of stools containing blood)
  7. Rectal haemorrhage (bleeding from anus)

40-49:

  1. Defaecation urgency (a sudden compelling urge to defecate)
  2. Depression
  3. Dysfunctional uterine bleeding
  4. Dyspnoea (difficult or laboured respiration)
  5. Emotional distress
  6. Facial pain
  7. Febrile neutropenia (fever with reduced white blood cells)
  8. Fistula (an abnormal connection or passageway between two)
  9. Gastrointestinal obstruction
  10. General physical health deterioration (weak health status)

50-59:

n/a

60+:

  1. Hypertension (high blood pressure)
  2. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  3. Depression
  4. General physical health deterioration (weak health status)
  5. Urinary tract infection
  6. Abdominal pain
  7. Anastomotic leak
  8. Arthralgia (joint pain)
  9. Atelectasis (partial or complete collapse of the lung)
  10. Benign neoplasm of thyroid gland (benign (non-cancerous) tumours of the thyroid gland)

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 7 people, 38.89%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.11%
  3. Sleep Disorder: 1 person, 5.56%
  4. Pneumonia: 1 person, 5.56%
  5. Pancreatic Insufficiency: 1 person, 5.56%
  6. Nausea (feeling of having an urge to vomit): 1 person, 5.56%
  7. Infection: 1 person, 5.56%
  8. Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 1 person, 5.56%
  9. High Blood Pressure: 1 person, 5.56%
  10. High Blood Cholesterol: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and Fortaz?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Profen and Fortaz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fortaz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Profen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fortaz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen and ceftazidime (the active ingredients of Profen and Fortaz, respectively), and Profen and Fortaz (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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