Profen and Gemtesa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Gemtesa (vibegron). Common drug interactions include urinary tract infection among females and hallucination among males.

The phase IV clinical study analyzes what interactions people have when they take Profen and Gemtesa. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Gemtesa?

Gemtesa has active ingredients of vibegron. eHealthMe is studying from 2,648 Gemtesa users. Check the latest studies of Gemtesa.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

27 people who take Profen and Gemtesa together, and have interactions are studied.

What are the common drug interactions of Profen and Gemtesa, by gender? *:

female:

Urinary tract infection
Asthma
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dizziness
Fall
Fibromyalgia (a long-term condition which causes pain all over the body)
Migraine (headache)
Multiple allergies (allergy to multiple agents)
Hypertension (high blood pressure)
Procedural pain

male:

Hallucination (an experience involving the perception of something not present)
Dizziness
Restlessness (not able to rest)
Confusional state
Delusion (a false belief or opinion)
Depression
Disease progression
Nonspecific reaction (unspecified reaction)
Parkinson's disease
Urinary retention postoperative

What are the common drug interactions of Profen and Gemtesa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Restlessness (not able to rest)

30-39:

n/a

40-49:

Asthma
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Fibromyalgia (a long-term condition which causes pain all over the body)
Migraine (headache)
Multiple allergies (allergy to multiple agents)
Hysterectomy

50-59:

Abdominal distension
Anxiety
Asthenia (weakness)
Cellulitis (infection under the skin)
Conjunctivitis (pink eye)
Eating disorder
Fall
Fungal infection
Gastric infection (infection of stomach)
Gastrointestinal disorder (functional problems of gastrointestinal tract)

60+:

Dizziness
Urinary tract infection
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Adverse drug reaction
Alopecia (absence of hair from areas of the body)
Balance disorder
Bladder discomfort
Blood folate decreased
Blood pressure increased
Bradycardia (abnormally slow heart action)

What are the existing conditions these people have? *

Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 5 people, 18.52%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 14.81%
High Blood Pressure: 3 people, 11.11%
Drowsiness: 3 people, 11.11%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 11.11%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 11.11%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 2 people, 7.41%
Muscle Spasms (muscle contraction): 2 people, 7.41%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 7.41%
Hypersensitivity: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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