Profen and Intal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Intal (cromolyn sodium). Common drug interactions include abdominal discomfort among females and swelling face among males.

The phase IV clinical study analyzes what interactions people have when they take Profen and Intal. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Intal?

Intal has active ingredients of cromolyn sodium. It is often used in asthma. eHealthMe is studying from 1,621 Intal users. Check the latest studies of Intal.



On Aug, 08, 2026

18 people who take Profen and Intal together, and have interactions are studied.

Profen and Intal drug interactions.

What are the common drug interactions of Profen and Intal, by gender? *:

female:

  1. Abdominal discomfort
  2. Anxiety
  3. Asthenia (weakness)
  4. Blood glucose decreased
  5. Chills (felling of cold)
  6. Cholecystitis chronic (long lasting infection of gallbladder)
  7. Cold sweat
  8. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  9. Disseminated tuberculosis
  10. Dyspnoea (difficult or laboured respiration)

male:

  1. Swelling face
  2. Abnormal dreams
  3. Anxiety
  4. Cough
  5. Dry skin
  6. Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
  7. Productive cough
  8. Pruritus generalised (generalized itching)
  9. Skin irritation

What are the common drug interactions of Profen and Intal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Tinnitus (a ringing in the ears)
  2. Herpes zoster oticus (viral infection of the inner, middle, and external ear caused by varicella-zoster virus (vzv))
  3. Vasculitis (inflammation of a blood vessel or blood vessels)
  4. Abdominal pain
  5. Diarrhoea
  6. Encephalitis (inflammation of the brain)
  7. Pyrexia (fever)
  8. Sensory disturbance (sense disturbance)
  9. Tremor (trembling or shaking movements in one or more parts of your body)
  10. Vomiting

20-29:

  1. Swelling face
  2. Anxiety
  3. Cholecystitis chronic (long lasting infection of gallbladder)
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Emotional distress
  6. Gallbladder injury
  7. General physical health deterioration (weak health status)
  8. Injury
  9. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  10. Nausea (feeling of having an urge to vomit)

30-39:

n/a

40-49:

  1. Cold sweat
  2. Disseminated tuberculosis
  3. Dyspnoea (difficult or laboured respiration)
  4. Haematuria (presence of blood in urine)
  5. Hypersensitivity
  6. Injection site haematoma (localized swelling filled with blood at injection site)
  7. Pyrexia (fever)
  8. Urethral injury
  9. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
  10. Vomiting projectile

50-59:

  1. Blood glucose decreased

60+:

  1. Abnormal dreams
  2. Anxiety
  3. Cough
  4. Dry skin
  5. Productive cough
  6. Pruritus generalised (generalized itching)
  7. Skin irritation

What are the existing conditions these people have? *

  1. High Blood Pressure: 2 people, 11.11%
  2. Bruton's Agammaglobulinaemia (low or completely absent levels of immunoglobulins in the bloodstream): 2 people, 11.11%
  3. Premenstrual Syndrome: 1 person, 5.56%
  4. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 5.56%
  5. Bladder Cancer: 1 person, 5.56%
  6. Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 5.56%
  7. Acne (skin problems that cause pimples): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and Intal?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Profen and Intal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Intal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Profen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Intal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen and cromolyn sodium (the active ingredients of Profen and Intal, respectively), and Profen and Intal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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