Profen and Oxytrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Oxytrol (oxybutyin). Common drug interactions include syncope among females and altered state of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Profen and Oxytrol. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Oxytrol?

Oxytrol has active ingredients of oxybutyin. It is often used in urge incontinence. eHealthMe is studying from 1,285 Oxytrol users. Check the latest studies of Oxytrol.

On Jul, 27, 2026

22 people who take Profen and Oxytrol together, and have interactions are studied.

What are the common drug interactions of Profen and Oxytrol, by gender? *:

female:

Syncope (loss of consciousness with an inability to maintain postural tone)
Temporal arteritis (inflammation and damage to blood vessels that supply the head area)
Thrombosis (formation of a blood clot inside a blood vessel)
Tooth infection
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Urinary tract infection
Vaginal burning sensation
Vaginal mycosis (vaginal fungal infection)
Colitis ulcerative (inflammation of colon with ulcer)
Haematochezia (passage of stools containing blood)

male:

Altered state of consciousness (altered state of mind)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Renal injury (kidney injury)
Stress
Colitis ulcerative (inflammation of colon with ulcer)
Haematochezia (passage of stools containing blood)
Irritable bowel syndrome
Drug ineffective
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Anxiety

What are the common drug interactions of Profen and Oxytrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Emotional distress
General physical health deterioration (weak health status)
Injury
Pulmonary embolism (blockage of the main artery of the lung)
Anxiety
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

30-39:

n/a

40-49:

Device failure
Injection site erythema (redness at injection site)
Injection site pruritus (severe itching at injection site)
Injection site reaction
Injection site swelling
Metrorrhagia (uterine bleeding at irregular intervals)
Rash
Tooth infection
Vaginal burning sensation
Vaginal mycosis (vaginal fungal infection)

50-59:

Cataract (clouding of the lens inside the eye)
Drug ineffective
Fracture
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Joint swelling
Post procedural complication
Rash generalised (rash on most of body parts)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Wound infection staphylococcal

60+:

Anxiety
Colitis ulcerative (inflammation of colon with ulcer)
Irritable bowel syndrome
Multi-organ failure (multisystem organ failure)
Oedema peripheral (superficial swelling)
Pain in extremity
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)
Stress
Adverse drug reaction

What are the existing conditions these people have? *

Urinary Incontinence (inability to control the flow of urine and involuntary urination): 4 people, 18.18%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 18.18%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 13.64%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 9.09%
High Blood Pressure: 2 people, 9.09%
High Blood Cholesterol: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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