Profen and Qutenza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Qutenza (capsaicin). Common drug interactions include application site pain among females and burning sensation among males.

The phase IV clinical study analyzes what interactions people have when they take Profen and Qutenza. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Qutenza?

Qutenza has active ingredients of capsaicin. eHealthMe is studying from 883 Qutenza users. Check the latest studies of Qutenza.



On Jul, 28, 2026

11 people who take Profen and Qutenza together, and have interactions are studied.

Profen and Qutenza drug interactions.

What are the common drug interactions of Profen and Qutenza, by gender? *:

female:

  1. Application site pain
  2. Application site erythema (redness of the skin at application site)
  3. Drug ineffective
  4. Drug tolerance decreased
  5. Neuralgia (pain in one or more nerves)
  6. Loss of consciousness
  7. Tremor (trembling or shaking movements in one or more parts of your body)
  8. Application site burn
  9. Application site discolouration
  10. Application site reaction

male:

  1. Burning sensation
  2. Application site pain
  3. Herpes zoster
  4. Hypertensive heart disease
  5. Merycism (a rare disease in which food is chewed, swallowed, and then returned to the mouth and chewed again)
  6. Quality of life decreased
  7. Rash pruritic (redness with itching)
  8. Sleep disorder
  9. Erythema (redness of the skin)
  10. Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system)

What are the common drug interactions of Profen and Qutenza, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system)

30-39:

n/a

40-49:

  1. Application site discolouration
  2. Application site reaction
  3. Application site scar
  4. Application site vesicles (small bubble within a cell at application site)
  5. Hypersensitivity
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Pruritus generalised (generalized itching)
  8. Urticaria (rash of round, red welts on the skin that itch intensely)
  9. Application site pain
  10. Application site erythema (redness of the skin at application site)

50-59:

  1. Loss of consciousness
  2. Tremor (trembling or shaking movements in one or more parts of your body)

60+:

  1. Application site pain
  2. Burning sensation

What are the existing conditions these people have? *

  1. Neuralgia (pain in one or more nerves): 3 people, 27.27%
  2. Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 2 people, 18.18%
  3. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 1 person, 9.09%
  4. Spinal Disorder (disease of spine a back bone): 1 person, 9.09%
  5. Post-Thoracotomy Pain Syndrome: 1 person, 9.09%
  6. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 1 person, 9.09%
  7. Intervertebral Disc Protrusion (spinal disc protrusion): 1 person, 9.09%
  8. Hypoaesthesia (reduced sense of touch or sensation): 1 person, 9.09%
  9. Gastric Ph Decreased: 1 person, 9.09%
  10. Essential Hypertension (primary hypertension): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and Qutenza?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Profen and Qutenza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Qutenza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Profen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Qutenza and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen and capsaicin (the active ingredients of Profen and Qutenza, respectively), and Profen and Qutenza (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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